Semi-automatic Download of Prostate Biopsy Cores While Keeping the Orientation, Unfolding and Unity of the Sample

NCT ID: NCT01692405

Last Updated: 2019-04-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

436 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-04-29

Study Completion Date

2017-04-24

Brief Summary

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Performance evaluation of a novel, semi-automated device and method for needle core biopsy download compared to standard methods in terms of:

1. Biopsy core length obtained (i.e. collecting all tissue fragments)
2. Biopsy core yield (i.e. percent of tissue loss during the pathologic processing)
3. Pathologist interpretability
4. Processing time
5. Prostate cancer detection.

Detailed Description

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Conditions

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Prostate Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Standard method

Standard method- shaking the biopsy needle into a formalin container.

Group Type NO_INTERVENTION

No interventions assigned to this group

Download onto a biopsy sponge pad

Samples will be downloaded by moving the needle notch on a biopsy sponge pad.

Group Type ACTIVE_COMPARATOR

biopsy sponge pad

Intervention Type PROCEDURE

the biopsy core is downloaded onto a biopsy sponge pad which is than entered into a biopsy cassette.

Dowloading the biopsy cores using NavigoBx system

Downloading the biopsy cores using NavigoBx™ system. The NaviGoBx™ device is intended for the retention of a biopsy specimen and for preservation of the specimen's in-needle location and orientation.

Group Type EXPERIMENTAL

NaviGo Bx™

Intervention Type DEVICE

The NaviGoBx™ system is a device and method that enables an accurate reporting of the exact longitudinal location and direction of the biopsy specimen along the needle notch as well as the accurate length of the specimen. Acquiring this information during the biopsy extraction session provides an accurate designation of the location of any later region of interest within the specimen itself to the longitudinal position along the needle mandrel.

Interventions

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NaviGo Bx™

The NaviGoBx™ system is a device and method that enables an accurate reporting of the exact longitudinal location and direction of the biopsy specimen along the needle notch as well as the accurate length of the specimen. Acquiring this information during the biopsy extraction session provides an accurate designation of the location of any later region of interest within the specimen itself to the longitudinal position along the needle mandrel.

Intervention Type DEVICE

biopsy sponge pad

the biopsy core is downloaded onto a biopsy sponge pad which is than entered into a biopsy cassette.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Age 18 years or older
* Planned for radical or open prostatectomy operation or Planned for TRUS prostate biopsy procedure.
* Signed informed consent.

Exclusion Criteria

* Patient's unwilling to participate.
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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UC Care, Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Haemek madical center

Afula, , Israel

Site Status

Countries

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Israel

References

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Obek C, Doganca T, Erdal S, Erdogan S, Durak H. Core length in prostate biopsy: size matters. J Urol. 2012 Jun;187(6):2051-5. doi: 10.1016/j.juro.2012.01.075. Epub 2012 Apr 11.

Reference Type BACKGROUND
PMID: 22498214 (View on PubMed)

Other Identifiers

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0086-12-EMC

Identifier Type: -

Identifier Source: org_study_id

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