Trial Outcomes & Findings for Nasal Pillows vs. Nasal Masks at High CPAP Pressure (NCT NCT01690923)

NCT ID: NCT01690923

Last Updated: 2014-10-08

Results Overview

AHI (measure of sleep-disordered breathing severity) on nasal mask and nasal pillows measured as average events/hour

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

20 participants

Primary outcome timeframe

7 days

Results posted on

2014-10-08

Participant Flow

Participants recruited from ResMed Science Centre, Sydney, between Aug 2011 and Aug 2012

Participant milestones

Participant milestones
Measure
Nasal Mask First, Then Pillows Mask
Sequence 1: Nasal mask first, then Pillows mask \[Nasal mask : Nasal mask (Mirage Activa, Micro, FX) Pillows mask : Nasal pillows mask (Swift FX)\]
Pillows Mask First, Then Nasal Mask
Sequence 2: Pillows mask first, then Nasal mask \[Nasal mask : Nasal mask (Mirage Activa, Micro, FX) Pillows mask : Nasal pillows mask (Swift FX)\]
Overall Study
STARTED
10
11
Overall Study
COMPLETED
10
10
Overall Study
NOT COMPLETED
0
1

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Nasal Pillows vs. Nasal Masks at High CPAP Pressure

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Current CPAP Users
n=20 Participants
Nasal mask; Pillows mask Nasal mask : Nasal mask (Mirage Activa, Micro, FX) Pillows mask : Nasal pillows mask (Swift FX)
Age, Categorical
<=18 years
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
8 Participants
n=5 Participants
Age, Categorical
>=65 years
12 Participants
n=5 Participants
Age, Continuous
64.6 years
STANDARD_DEVIATION 9.5 • n=5 Participants
Sex: Female, Male
Female
5 Participants
n=5 Participants
Sex: Female, Male
Male
15 Participants
n=5 Participants
Region of Enrollment
Australia
20 participants
n=5 Participants

PRIMARY outcome

Timeframe: 7 days

AHI (measure of sleep-disordered breathing severity) on nasal mask and nasal pillows measured as average events/hour

Outcome measures

Outcome measures
Measure
Current CPAP Users
n=20 Participants
Nasal mask; Pillows mask Nasal mask : Nasal mask (Mirage Activa, Micro, FX) Pillows mask : Nasal pillows mask (Swift FX)
AHI on Nasal Mask and Pillows Mask
AHI on nasal mask
1.7 events/hour
Standard Deviation 1.1
AHI on Nasal Mask and Pillows Mask
AHI on Nasal pillows
1.9 events/hour
Standard Deviation 1.3

SECONDARY outcome

Timeframe: After 7 days of use

Participant's feedback of performance of the study devices. Likert Scale 0-10 (0=very bad, 10=very good)

Outcome measures

Outcome measures
Measure
Current CPAP Users
n=20 Participants
Nasal mask; Pillows mask Nasal mask : Nasal mask (Mirage Activa, Micro, FX) Pillows mask : Nasal pillows mask (Swift FX)
Usability
Subjective Scores Overall Performance-Nasal Mask
8.0 Units on a scale
Interval 7.25 to 9.75
Usability
Subjective Scores Overall Performance-Nasal Pillow
8.5 Units on a scale
Interval 7.0 to 9.0

Adverse Events

Current CPAP Users

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Xueling Zhu, Clinical Consultant

ResMed Ltd

Phone: 61288842265

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place