Prevention for Positives: An RCT Among Vietnamese HIV-positive IDU
NCT ID: NCT01689545
Last Updated: 2014-06-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
2175 participants
INTERVENTIONAL
2007-12-31
2013-04-30
Brief Summary
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Detailed Description
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1. What is the impact of perceived HIV-related stigma on disclosure, social support, and coping among IDUs?
2. What roles do disclosure, social support, and coping play in facilitating the reduction of HIV-risk behaviors
3. Are combined individual and structural level interventions more effective in reducing injecting and sexual behaviors among HIV-positive IDUs than individual or structural interventions alone and more effective than the standard HIV VCT?
Conditions
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Study Design
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RANDOMIZED
FACTORIAL
PREVENTION
TRIPLE
Study Groups
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Individual level
Individual level
Index participants will participate in standard HIV VCT supplemented with 2 posttest counseling sessions, followed by 2 post-test skill-building support groups for HIV positive IDUs.
Structural level standard of care
Posters and billboards on HIV/AIDS transmission, leaflets on HIV/AIDS transmission available in health station, 15-minute monthly public broadcasts (via the village loudspeaker) on the consequences of HIV/AIDS and the number of HIV cases in the country and province will be delivered in communities.
Structural level
Structural level
Community members will participate in 2 community-based HIV and IDU stigma videos combined with a series of visits with community outreach workers.
Individual level standard of care
The education materials that are currently offered in Thai Nguyen will be delivered didactically by health workers on 1) the HIV situation in Vietnam; 2) consequences of drug use; 3) routes of HIV transmission; and 4) options for drug treatment.
Combined individual & structural level
Individual level
Index participants will participate in standard HIV VCT supplemented with 2 posttest counseling sessions, followed by 2 post-test skill-building support groups for HIV positive IDUs.
Structural level
Community members will participate in 2 community-based HIV and IDU stigma videos combined with a series of visits with community outreach workers.
Standard of Care
Individual level standard of care
The education materials that are currently offered in Thai Nguyen will be delivered didactically by health workers on 1) the HIV situation in Vietnam; 2) consequences of drug use; 3) routes of HIV transmission; and 4) options for drug treatment.
Structural level standard of care
Posters and billboards on HIV/AIDS transmission, leaflets on HIV/AIDS transmission available in health station, 15-minute monthly public broadcasts (via the village loudspeaker) on the consequences of HIV/AIDS and the number of HIV cases in the country and province will be delivered in communities.
Interventions
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Individual level
Index participants will participate in standard HIV VCT supplemented with 2 posttest counseling sessions, followed by 2 post-test skill-building support groups for HIV positive IDUs.
Structural level
Community members will participate in 2 community-based HIV and IDU stigma videos combined with a series of visits with community outreach workers.
Individual level standard of care
The education materials that are currently offered in Thai Nguyen will be delivered didactically by health workers on 1) the HIV situation in Vietnam; 2) consequences of drug use; 3) routes of HIV transmission; and 4) options for drug treatment.
Structural level standard of care
Posters and billboards on HIV/AIDS transmission, leaflets on HIV/AIDS transmission available in health station, 15-minute monthly public broadcasts (via the village loudspeaker) on the consequences of HIV/AIDS and the number of HIV cases in the country and province will be delivered in communities.
Eligibility Criteria
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Inclusion Criteria
* able and wiling to bring an injecting network member for screening
* injected drugs in previous 6 months
* planned residence in Thai Nguyen for next 24 months
* laboratory confirmed HIV negative diagnosis
* injected or shared drug paraphernalia in past 6 months
* interacts at least once a week with index participant
Exclusion Criteria
* unable to participate in group counseling sessions due to psychological disturbance, cognitive impairment or threatening behavior
* currently participating in other HIV or drug use intervention activities
Network member participant
* unwilling to provide locator information
* having psychological or cognitive impairment
* currently participating in other HIV intervention
18 Years
MALE
No
Sponsors
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Johns Hopkins Bloomberg School of Public Health
OTHER
Responsible Party
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Principal Investigators
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Vivian F Go, PhD
Role: PRINCIPAL_INVESTIGATOR
Johns Hopkins Bloomberg School of Public Health
Locations
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Center for Preventive Medicine
Thái Nguyên, Thai Nguyen, Vietnam
Countries
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References
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Levintow SN, Pence BW, Powers KA, Sripaipan T, Ha TV, Chu VA, Quan VM, Latkin CA, Go VF. Estimating the Effect of Depression on HIV Transmission Risk Behaviors Among People Who Inject Drugs in Vietnam: A Causal Approach. AIDS Behav. 2021 Feb;25(2):438-446. doi: 10.1007/s10461-020-03007-9.
Levintow SN, Pence BW, Ha TV, Le Minh N, Sripaipan T, Latkin CA, Vu PT, Quan VM, Frangakis C, Go VF. Depressive Symptoms at HIV Testing and Two-Year All-Cause Mortality Among Men Who Inject Drugs in Vietnam. AIDS Behav. 2019 Mar;23(3):609-616. doi: 10.1007/s10461-018-2318-8.
Go VF, Frangakis C, Minh NL, Latkin C, Ha TV, Mo TT, Sripaipan T, Davis WW, Zelaya C, Vu PT, Celentano DD, Quan VM. Efficacy of a Multi-level Intervention to Reduce Injecting and Sexual Risk Behaviors among HIV-Infected People Who Inject Drugs in Vietnam: A Four-Arm Randomized Controlled Trial. PLoS One. 2015 May 26;10(5):e0125909. doi: 10.1371/journal.pone.0125909. eCollection 2015.
Other Identifiers
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