Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
12 participants
INTERVENTIONAL
2012-02-29
2012-04-30
Brief Summary
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Detailed Description
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Twelve elderly males with chronic heart failure, New York Heart Association class I-II, will participate in this study. Participants will be allocated into two equally-sized groups: a stair descending group (n = 6) and a stair ascending group (n = 6). At the beginning of the study, the volunteers will perform an acute bout of stair descending or stair ascending exercise on an automatic escalator (4 sets of 3 min each, speed will be set at 45 steps∙min-1). Step height will be 20.5 mm. Before and at day 2 post exercise, physiologic measurements will be performed and blood samples will be collected. Then, participants will carry out six weeks of stair descending or ascending training consisting of three exercise sessions per week (the first two weeks the speed will be set at 45 steps∙min-1, the next two weeks at 50 steps∙min-1 and the last two weeks at 55 steps∙min-1 for both groups). Afterward, they will repeat the acute stair descending or ascending protocol, as carried out at the beginning of the study, and the same physiologic measurements will be performed and blood samples will be collected.
Measurements:
Isometric (at 90 knee flexion), concentric and eccentric peak torque at 60o∙s-1of quadriceps femoris, pain-free range of motion, delayed onset muscle soreness and creatine kinase will be measured.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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Stair descending group
Stair descending exercise. Participants will carry out six weeks of stair descending training consisting of three exercise sessions per week.
Exercise
Comparison between stair descending and stair ascending training
Stair ascending group
Stair ascending exercise. Participants will carry out six weeks of stair descending training consisting of three exercise sessions per week.
Exercise
Comparison between stair descending and stair ascending training
Interventions
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Exercise
Comparison between stair descending and stair ascending training
Eligibility Criteria
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Inclusion Criteria
* subject provides written informed consent
* personal physician of the participants provides written informed consent
Exclusion Criteria
* consumed any nutritional supplement the last 3 months
* performed intense eccentric exercise the last 6 months
* non Caucasian
60 Years
70 Years
MALE
No
Sponsors
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University of Thessaly
OTHER
Aristotle University Of Thessaloniki
OTHER
European University Cyprus
OTHER
Responsible Party
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Dr. Anastasios Theodorou
Principal investigator
Principal Investigators
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George Panayiotou, PhD
Role: STUDY_CHAIR
Research Centre, European University Cyprus
Locations
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European University Cyprus
Nicosia, , Cyprus
Countries
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References
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Paschalis V, Nikolaidis MG, Theodorou AA, Panayiotou G, Fatouros IG, Koutedakis Y, Jamurtas AZ. A weekly bout of eccentric exercise is sufficient to induce health-promoting effects. Med Sci Sports Exerc. 2011 Jan;43(1):64-73. doi: 10.1249/MSS.0b013e3181e91d90.
Other Identifiers
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EUC-011
Identifier Type: -
Identifier Source: org_study_id