An Observational Study To Assess Liver Fibrosis Stages in Patients With Chronic Hepatitis C Infection

NCT ID: NCT01671046

Last Updated: 2016-11-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

123 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-07-31

Study Completion Date

2015-12-31

Brief Summary

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This multi-center, prospective observational study will evaluate the correlation of liver biopsy and transient elastography in liver fibrosis assessment in patients with chronic hepatitis C. Data will be collected for 96 weeks.

Detailed Description

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Conditions

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Hepatitis C, Chronic

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Cohort

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Adult patients, \>/= 18 years of age
* Chronic Hepatitis C infection (mono-infection or co-infection with human immunodeficiency virus \[HIV\])
* Detectable level of hepatitis C RNA
* Initiating treatment with pegylated interferon plus ribavirin, or pegylated interferon plus ribavirin, and boceprevir or telaprevir according to local guidelines
* Last liver biopsy performed no later than 3 months prior to enrolment to study

Exclusion Criteria

* Co-infection with hepatitis B virus
* Previous treatment with pegylated interferon and ribavirin
* Participation in another clinical study in the last 12 months prior to study start
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hoffmann-La Roche

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Clinical Trials

Role: STUDY_DIRECTOR

Hoffmann-La Roche

Locations

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Rio de Janeiro, Rio de Janeiro, Brazil

Site Status

Rio de Janeiro, Rio de Janeiro, Brazil

Site Status

Botucatu, São Paulo, Brazil

Site Status

Campinas, São Paulo, Brazil

Site Status

Campinas, São Paulo, Brazil

Site Status

Santo André, São Paulo, Brazil

Site Status

São Paulo, São Paulo, Brazil

Site Status

São Paulo, São Paulo, Brazil

Site Status

São Paulo, São Paulo, Brazil

Site Status

Sorocaba, São Paulo, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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ML27944

Identifier Type: -

Identifier Source: org_study_id