Trial Outcomes & Findings for Zero Heat Flux Thermometry System Comparison Trial (NCT NCT01670760)

NCT ID: NCT01670760

Last Updated: 2020-09-22

Results Overview

Body temperature difference as defined by Agreement (bias - Zero heat flux thermometry minus nasopharyngeal) between simultaneously-acquired nasopharyngeal and forehead deep tissue temperatures as assessed by Bland and Altman repeated measures technique.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

20 participants

Primary outcome timeframe

Every 5 to 10 minutes, or as clinically indicated, for the duration of the surgery from the time of incision to the time of closure. The average duration of surgery was 57 minutes.

Results posted on

2020-09-22

Participant Flow

Participant milestones

Participant milestones
Measure
Zero-Heat-Flux
This is a single arm study. All patients will have deep tissue temperature monitored from the nasopharyngeal and lateral forehead sites simultaneously. Zero-heat-flux thermometry: The zero-heat-flux thermometer will be placed on the subject's lateral forehead for the duration of the surgery to measure deep tissue temperature.
Overall Study
STARTED
20
Overall Study
COMPLETED
20
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Zero Heat Flux Thermometry System Comparison Trial

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Zero-Heat-Flux
n=20 Participants
This is a single arm study. All patients will have deep tissue temperature monitored from the nasopharyngeal and lateral forehead sites simultaneously. Zero-heat-flux thermometry: The zero-heat-flux thermometer will be placed on the subject's lateral forehead for the duration of the surgery to measure deep tissue temperature.
Age, Categorical
<=18 years
20 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
0 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
Age, Continuous
7.1 years
STANDARD_DEVIATION 5.0 • n=5 Participants
Sex: Female, Male
Female
4 Participants
n=5 Participants
Sex: Female, Male
Male
16 Participants
n=5 Participants
Region of Enrollment
United States
20 participants
n=5 Participants

PRIMARY outcome

Timeframe: Every 5 to 10 minutes, or as clinically indicated, for the duration of the surgery from the time of incision to the time of closure. The average duration of surgery was 57 minutes.

Body temperature difference as defined by Agreement (bias - Zero heat flux thermometry minus nasopharyngeal) between simultaneously-acquired nasopharyngeal and forehead deep tissue temperatures as assessed by Bland and Altman repeated measures technique.

Outcome measures

Outcome measures
Measure
Zero-Heat-Flux
n=247 Observation
This is a single arm study. All patients will have deep tissue temperature monitored from the nasopharyngeal and lateral forehead sites simultaneously. Zero-heat-flux thermometry: The zero-heat-flux thermometer will be placed on the subject's lateral forehead for the duration of the surgery to measure deep tissue temperature.
Body Temperature Difference in Degrees Celsius
-0.28 Degrees Celsius
Standard Error 0.027

Adverse Events

Zero-Heat-Flux

Serious events: 0 serious events
Other events: 11 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure
Zero-Heat-Flux
n=20 participants at risk
This is a single arm study. All patients will have deep tissue temperature monitored from the nasopharyngeal and lateral forehead sites simultaneously. Zero-heat-flux thermometry: The zero-heat-flux thermometer will be placed on the subject's lateral forehead for the duration of the surgery to measure deep tissue temperature.
Skin and subcutaneous tissue disorders
Redness at attachment site
55.0%
11/20 • Number of events 11 • For the duration of the surgery from the time of incision to the time of closure. The average duration of surgery was 57 minutes.

Additional Information

Terri White

3M

Phone: 651-733-0228

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place