Trial Outcomes & Findings for SCD Use to Prevent Deep Venous Thrombosis (DVT) in Patients With PICC Lines (NCT NCT01670188)

NCT ID: NCT01670188

Last Updated: 2018-01-09

Results Overview

Ultrasonographically-confirmed upper extremity venous thrombosis (symptomatic and asymptomatic) in arm with PICC catheter

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

78 participants

Primary outcome timeframe

baseline to 14 days post insertion of PICC line

Results posted on

2018-01-09

Participant Flow

Patients requiring placement of a peripherally inserted central catheter (PICC) line in the neuroscience intensive care unit were recruited at Mayo Clinic in Rochester, Minnesota.

One patient randomized to the non-SCD arm died before the first ultrasound could be obtained and therefore could not be entered into the analysis.

Participant milestones

Participant milestones
Measure
Pneumatic SCD
Use of pneumatic sequential compression device (SCD) (VenaFlow System - DJO Global) on upper extremity with peripherally inserted central catheter (PICC) line inserted.
Non-SCD Group
Patients enrolled in this group received standard care.
Overall Study
STARTED
38
40
Overall Study
COMPLETED
38
39
Overall Study
NOT COMPLETED
0
1

Reasons for withdrawal

Reasons for withdrawal
Measure
Pneumatic SCD
Use of pneumatic sequential compression device (SCD) (VenaFlow System - DJO Global) on upper extremity with peripherally inserted central catheter (PICC) line inserted.
Non-SCD Group
Patients enrolled in this group received standard care.
Overall Study
Death
0
1

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Pneumatic SCD
n=38 Participants
Use of pneumatic sequential compression device (SCD) (VenaFlow System - DJO Global) on upper extremity with peripherally inserted central catheter (PICC) line inserted.
Non-SCD Group
n=39 Participants
Patients enrolled in this group received standard care.
Total
n=77 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=38 Participants
0 Participants
n=39 Participants
0 Participants
n=77 Participants
Age, Categorical
Between 18 and 65 years
27 Participants
n=38 Participants
29 Participants
n=39 Participants
56 Participants
n=77 Participants
Age, Categorical
>=65 years
11 Participants
n=38 Participants
10 Participants
n=39 Participants
21 Participants
n=77 Participants
Sex: Female, Male
Female
23 Participants
n=38 Participants
26 Participants
n=39 Participants
49 Participants
n=77 Participants
Sex: Female, Male
Male
15 Participants
n=38 Participants
13 Participants
n=39 Participants
28 Participants
n=77 Participants
Race and Ethnicity Not Collected
0 Participants
Race and Ethnicity were not collected from any participant.
Region of Enrollment
United States
38 participants
n=38 Participants
39 participants
n=39 Participants
77 participants
n=77 Participants

PRIMARY outcome

Timeframe: baseline to 14 days post insertion of PICC line

Ultrasonographically-confirmed upper extremity venous thrombosis (symptomatic and asymptomatic) in arm with PICC catheter

Outcome measures

Outcome measures
Measure
Pneumatic SCD
n=38 Participants
Use of pneumatic sequential compression device (SCD) (VenaFlow System - DJO Global) on upper extremity with peripherally inserted central catheter (PICC) line inserted.
Non-SCD Group
n=39 Participants
Patients enrolled in this group received standard care.
Number of Patients Who Experienced an Ultrasonographically-confirmed Venous Thrombosis
13 Participants
5 Participants

Adverse Events

Pneumatic SCD

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Non-SCD Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Alejandro Rabinstein

Mayo Clinic

Phone: 507-284-4741

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place