Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
327 participants
OBSERVATIONAL
2012-10-01
2020-12-16
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Study Groups
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Subjects with cancer and ONJ
Subjects with cancer and positively adjudicated ONJ
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Newly diagnosed, positively-adjudicated ONJ
* ECOG \<=2 and expected survival ≥3 months
* Willing to provide access to previous and future medical and dental information
* Subject or subject's legally acceptable representative has provided written informed consent
Exclusion Criteria
* Subject will not be available for protocol required study visits, to the best of the subject and investigator's knowledge.
* Subject has any kind of disorder that, in the opinion of the investigator, may compromise the ability of the subject to give written informed consent and/or to comply with all required study procedures.
18 Years
ALL
No
Sponsors
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Amgen
INDUSTRY
Responsible Party
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Principal Investigators
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MD
Role: STUDY_DIRECTOR
Amgen
Locations
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Research Site
Beverly Hills, California, United States
Research Site
Duarte, California, United States
Research Site
Denver, Colorado, United States
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Farmington, Connecticut, United States
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Stratford, Connecticut, United States
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Washington D.C., District of Columbia, United States
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Gainesville, Florida, United States
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Atlanta, Georgia, United States
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Chicago, Illinois, United States
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Council Bluffs, Iowa, United States
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Baltimore, Maryland, United States
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Omaha, Nebraska, United States
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Omaha, Nebraska, United States
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Buffalo, New York, United States
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Buffalo, New York, United States
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Mineola, New York, United States
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Charlotte, North Carolina, United States
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Cleveland, Ohio, United States
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Philadelphia, Pennsylvania, United States
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Memphis, Tennessee, United States
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Nashville, Tennessee, United States
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Houston, Texas, United States
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Brussels, , Belgium
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Edegem, , Belgium
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Leuven, , Belgium
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Halifax, Nova Scotia, Canada
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Greater Sudbury, Ontario, Canada
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Kitchener, Ontario, Canada
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Sault Ste. Marie, Ontario, Canada
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Québec, Quebec, Canada
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Aarhus C, , Denmark
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København Ø, , Denmark
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Helsinki, , Finland
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Kuopio, , Finland
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Oulu, , Finland
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Bordeaux, , France
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Brest, , France
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Lyon, , France
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Paris, , France
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Saint-Herblain, , France
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Berlin, , Germany
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Berlin, , Germany
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Cologne, , Germany
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Düsseldorf, , Germany
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Mühlhausen, , Germany
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München, , Germany
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München, , Germany
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Regensburg, , Germany
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Athens, , Greece
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Athens, , Greece
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Thessaloniki, , Greece
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Thessaloniki, , Greece
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Alessandria, , Italy
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Brescia, , Italy
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Lecce, , Italy
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Roma, , Italy
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Torino, , Italy
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Seville, Andalusia, Spain
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Barcelona, Catalonia, Spain
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Madrid, , Spain
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Madrid, , Spain
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Cardiff, , United Kingdom
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London, , United Kingdom
Research Site
Sheffield, , United Kingdom
Countries
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References
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Schiodt M, Vadhan-Raj S, Chambers MS, Nicolatou-Galitis O, Politis C, Coropciuc R, Fedele S, Jandial D, Zhang J, Ma H, Saunders DP. A multicenter case registry study on medication-related osteonecrosis of the jaw in patients with advanced cancer. Support Care Cancer. 2018 Jun;26(6):1905-1915. doi: 10.1007/s00520-017-4003-2. Epub 2017 Dec 23.
Related Links
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AmgenTrials clinical trials website
Other Identifiers
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20101102
Identifier Type: -
Identifier Source: org_study_id