Evaluation of the Zilver® Vena™ Venous Stent

NCT ID: NCT01663051

Last Updated: 2016-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

35 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-11-30

Study Completion Date

2016-07-31

Brief Summary

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This prospective, non-randomized, multi-center study is intended to evaluate the Zilver® Vena™ stent in the treatment of symptomatic iliofemoral venous outflow obstruction.

Detailed Description

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Conditions

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Iliofemoral Venous Outflow Obstruction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Stent

Stent

Zilver Vena Venous Stent

Intervention Type DEVICE

Stenting iliofemoral venous outflow obstruction

Interventions

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Zilver Vena Venous Stent

Stenting iliofemoral venous outflow obstruction

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Symptomatic venous outflow obstruction in up to two iliofemoral venous segments (one in each limb), demonstrated by:
* CEAP 'C' ≥ 3, or
* VCSS pain score ≥ 2

Exclusion Criteria

* \< 18 years of age
* Pregnant or planning to become pregnant in the next 12 months
* Planned surgical or interventional procedures (except thrombolysis and thrombectomy in preparation for the procedure or vena cava filter placement prior to stent implantation in patients at high risk for pulmonary embolism) within 30 days prior to or after the study procedure.
* Lesions with intended treatment lengths extending into the inferior vena cava or below the level of the lesser trochanter
* Previous stenting of the target vessel
* Iliofemoral venous segment unsuitable for treatment with available sizes of study devices
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cook Group Incorporated

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Klinikum Arnsberg GmbH

Arnsberg, , Germany

Site Status

Galway University Hospitals

Galway, , Ireland

Site Status

Hospital Madrid Monteprincipe

Madrid, , Spain

Site Status

Kantonsspital Winterthur

Winterthur, , Switzerland

Site Status

Guy's and St Thomas' Hospital

London, , United Kingdom

Site Status

Countries

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Denmark Germany Ireland Spain Switzerland United Kingdom

References

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O'Sullivan GJ, Waldron D, Mannion E, Keane M, Donnellan PP. Thrombolysis and iliofemoral vein stent placement in cancer patients with lower extremity swelling attributed to lymphedema. J Vasc Interv Radiol. 2015 Jan;26(1):39-45. doi: 10.1016/j.jvir.2014.10.010.

Reference Type DERIVED
PMID: 25541444 (View on PubMed)

O'Sullivan GJ, Sheehan J, Lohan D, McCann-Brown JA. Iliofemoral venous stenting extending into the femoral region: initial clinical experience with the purpose-designed Zilver Vena stent. J Cardiovasc Surg (Torino). 2013 Apr;54(2):255-61.

Reference Type DERIVED
PMID: 23558660 (View on PubMed)

Other Identifiers

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10-018

Identifier Type: -

Identifier Source: org_study_id