Randomized Study of Failed SCS Trials Comparing Outcomes Using the Observational Mechanical Gateway (OMG) Connector

NCT ID: NCT01643213

Last Updated: 2020-11-13

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

27 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-07-31

Study Completion Date

2015-02-28

Brief Summary

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The purpose of this study is to evaluate patient preference of the Boston Scientific Corporation (BSC) commercially approved spinal cord stimulation (SCS) systems with the Observational Mechanical Gateway (OMG) in patients who failed non-BSC SCS trial therapy.

Detailed Description

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Spinal cord stimulation (SCS) is an established therapy for the treatment of chronic pain of the trunk and/or limbs. Standard practice includes a screening trial, typically lasting from 3 days to 7 days or more, for both the physician and the patient to evaluate whether SCS therapy is appropriate for permanent implantation. Screening trial success (hereafter referred to as a trial) is often considered predictive of long-term success of the therapy, although that has never been definitively demonstrated.

Boston Scientific Corporation (BSC) developed the Observational Mechanical Gateway (OMG) connectors to allow patients who previously underwent an SCS trial using Medtronic or St Jude Medical leads, operating room cables (OR-cables), and external trial stimulators (ETSs), to be able to connect to BSC commercially approved Spinal Cord Stimulation (SCS) trial systems to evaluate the BSC SCS therapy in the physician office setting prior to removal of the non-BSC leads.

Conditions

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Chronic Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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BSC approved SCS Trial Therapy w/ OMG

Precision Plus SCS Trial Therapy w/ OMG. Spinal cord stimulation (SCS) trial therapy activated using FDA-approved BSC SCS trial systems with the Observational Mechanical Gateway(OMG) to connect to non-BSC lead(s)

Group Type EXPERIMENTAL

BSC approved SCS Trial Therapy w/ OMG

Intervention Type DEVICE

No procedures will be attempted as part of this study. This intervention refers to connection and activation of all Boston Scientific commercially approved SCS trial systems for 30 minutes of SCS therapy for pain

Non Boston Scientific SCS Trial Therapy

Non Boston Scientific SCS Trial Therapy. Spinal cord stimulation (SCS) trial therapy activated using FDA-approved non BSC SCS system that the subject was implanted with, and received SCS therapy from, prior to study enrollment

Group Type ACTIVE_COMPARATOR

Non Boston Scientific SCS Trial Therapy

Intervention Type DEVICE

No procedures will be attempted as part of this study. This intervention refers to connection and activation of a previously implanted and programmed FDA-approved non Boston Scientific SCS trial system for 30 minutes of SCS therapy for pain

Interventions

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Non Boston Scientific SCS Trial Therapy

No procedures will be attempted as part of this study. This intervention refers to connection and activation of a previously implanted and programmed FDA-approved non Boston Scientific SCS trial system for 30 minutes of SCS therapy for pain

Intervention Type DEVICE

BSC approved SCS Trial Therapy w/ OMG

No procedures will be attempted as part of this study. This intervention refers to connection and activation of all Boston Scientific commercially approved SCS trial systems for 30 minutes of SCS therapy for pain

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Chronic intractable pain of the trunk and/or lower extremities
* History of trunk and/or lower extremity pain lasting at least 6 months
* Study candidate completed a spinal cord stimulation (SCS) trial of a FDA-approved non-Boston Scientific Corporation (non-BSC) system, exclusively for the treatment of chronic intractable pain of the trunk and/or lower extremities, that will not proceed to permanent implantation due to unsatisfactory treatment or in the physician's opinion received sub-optimal results
* Currently implanted with FDA-approved non-BSC SCS lead(s) exclusively in the thoracolumbar epidural space that are temporarily anchored for non-surgical removal at the termination of the screening trial period and which are approved for use with either the Observational Mechanical Gateway (OMG) A or OMG-M, per the OMG directions for use

Exclusion Criteria

* Primary source of pain is cancer-related, pelvic, visceral or angina
* Investigator-suspected gross lead migration during the non-BSC trial period which may preclude the study candidate from receiving adequate SCS therapy
* Study candidate reports \<10% paresthesia coverage of overall pain while running the preferred stimulation settings on the non-BSC SCS system at the end of the non-BSC SCS screening trial period
* Study candidate unwilling to tolerate implantation with an SCS system
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Boston Scientific Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Roshini Jain

Role: STUDY_DIRECTOR

Boston Scientific Corporation

Locations

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Hope Research Institute

Phoenix, Arizona, United States

Site Status

Neurovations

Napa, California, United States

Site Status

Comprehensive Pain Specialists

Broomfield, Colorado, United States

Site Status

Coastal Orthopedics and Sports Medicine of Southwest Florida, PA

Bradenton, Florida, United States

Site Status

Southeastern Integrated Medical

Gainesville, Florida, United States

Site Status

Compass Research, LLC

Orlando, Florida, United States

Site Status

Rush University Medical Center

Chicago, Illinois, United States

Site Status

Global Scientific Innovations - Advanced Pain Care Clinic

Evansville, Indiana, United States

Site Status

Columbia Interventional Pain Center

Columbia, Missouri, United States

Site Status

Southern New York NeuroSurgical Group

Johnson City, New York, United States

Site Status

New York Spine and Wellness Center

North Syracuse, New York, United States

Site Status

Riverhills Healthcare Incorporated

Cincinnati, Ohio, United States

Site Status

West Virginia University Hospitals

Morgantown, West Virginia, United States

Site Status

Countries

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United States

Other Identifiers

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A7006

Identifier Type: OTHER

Identifier Source: secondary_id

A7006

Identifier Type: -

Identifier Source: org_study_id