Digestive Tract Reconstruction After Gastrectomy of Gastric Cancer With Type 2 Diabetes

NCT ID: NCT01637350

Last Updated: 2016-02-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-08-31

Study Completion Date

2016-12-31

Brief Summary

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Different digestive tract reconstruction will affect the blood glucose level of gastric cancer with type 2 diabetes. Subtotal gastrectomy with Billroth II reconstruction and total gastrectomy with Roux-en-Y reconstruction may help to improve glycaemic control which includes fasting blood glucose, postprandial blood glucose, glycosylated hemoglobin, C -peptide and body weight of gastric cancer patients with type 2 diabetes.

Detailed Description

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Different digestive tract reconstruction will affect the blood glucose level of gastric cancer with type 2 diabetes. Subtotal gastrectomy with Billroth II reconstruction and total gastrectomy with Roux-en-Y reconstruction may help to improve glycaemic control which includes fasting blood glucose, postprandial blood glucose, glycosylated hemoglobin, C -peptide and body weight of gastric cancer patients with type 2 diabetes.

The investigators will observed fasting blood glucose, postprandial blood glucose, glycosylated hemoglobin, C -peptide and body weight of the patients preoperation, 14 days postoperation 3 month and 6month postoperation. The investigators will observed the effect of blood glucose to different digestive tract reconstruction after gastrectomy of gastric cancer with type 2 diabetes

Conditions

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Gastric Cancer

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Subtotal gastrectomy , BillrothⅠ

digestive tract reconstruction

Intervention Type PROCEDURE

Subtotal gastrectomy with BillrothⅠ or BillrothⅡ, total gastrectomy with jejunal interposition or Roux-en-Y reconstruction

Subtotal gastrectomy , BillrothⅡ

digestive tract reconstruction

Intervention Type PROCEDURE

Subtotal gastrectomy with BillrothⅠ or BillrothⅡ, total gastrectomy with jejunal interposition or Roux-en-Y reconstruction

total gastrectomy, jejunal interposition

digestive tract reconstruction

Intervention Type PROCEDURE

Subtotal gastrectomy with BillrothⅠ or BillrothⅡ, total gastrectomy with jejunal interposition or Roux-en-Y reconstruction

total gastrectomy , Roux-en-Y

digestive tract reconstruction

Intervention Type PROCEDURE

Subtotal gastrectomy with BillrothⅠ or BillrothⅡ, total gastrectomy with jejunal interposition or Roux-en-Y reconstruction

Interventions

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digestive tract reconstruction

Subtotal gastrectomy with BillrothⅠ or BillrothⅡ, total gastrectomy with jejunal interposition or Roux-en-Y reconstruction

Intervention Type PROCEDURE

Other Intervention Names

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no other names

Eligibility Criteria

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Inclusion Criteria

1. 18-75 years old,gastric cancer ,can be performed operation
2. with type 2 diabetes,fasting blood glucose \> 6.1mmol/L
3. without serious underlying diseases which may affect the metabolism and nutrient uptake
4. without serious underlying diseases which may affect anesthesia and operation
5. can be performed subtotal or total gastrectomy, predicted survival period \> 6months
6. no other abdominal operation
7. preoperation consultation
8. informed consent

Exclusion Criteria

1. recurrent,metastasis or die
2. patient requests for quit
3. pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tianjin Medical University Cancer Institute and Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Zhao Yan, Doctor

Role: STUDY_DIRECTOR

Tianjin Medical University Cancer Institute and Hospital

Locations

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Tianjin Medical University Cancer Institute and Hospital

Tianjin, Tianjin Municipality, China

Site Status

Countries

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China

Other Identifiers

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CIH-WXN-201205001

Identifier Type: -

Identifier Source: org_study_id

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