Evaluation of Transfer Kinematics and Kinetics in Patients Chronic Post-stroke Using the Tibion Bionic Leg

NCT ID: NCT01626417

Last Updated: 2012-11-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-05-31

Study Completion Date

2012-11-30

Brief Summary

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The objective of this clinical study is to examine the acute kinematics and kinetics of utilizing the Tibion Bionic Leg in a sample of chronic post-stroke patients performing sit-to-stand and stand-to-sit transfers across a range of assistance and resistance settings (internal to the device); to compare these metrics to baseline performance without the Bionic Leg; and to determine the Bionic Leg settings that optimize a restorative (equal force distribution) movement state in these patients.

Detailed Description

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Comprehensive motion (kinetics and kinematics) data specific to sit-to-stand and stand-to-sit transfers with and without the Tibion Bionic Leg. The Vicon Motion Analysis System will be utilized to track movement using markers on the subject and the Bionic Leg per the UCSF Human Performance Center's routine. Once outfitted with the marker system, patients will be instructed to perform multiple sit-to-stand and stand-to-sit transfers while data is gathered.

The sit-to-stand and stand-to-sit transfers will be performed using a standard chair, with a seat height not less than 12" from the floor. The chair will be positioned such that, at sitting rest, each of the subject's feet are positioned on limb-specific force plates (left and right).

Conditions

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Stroke

Keywords

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Stroke Tibion Bionics Rehab Therapy Robotics Intention

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Blinding Strategy

NONE

Study Groups

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Patient Population

Chronic post-stroke subjects with varied impairment level, who have completed routine rehabilitative physical therapy.

Group Type NO_INTERVENTION

Tibion Bionic Leg

Intervention Type DEVICE

The device is a lightweight, wearable, portable, battery-powered, robotic leg orthosis that provides active assistance and resistance to lower limb movement according to the patient's intent to move.

Interventions

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Tibion Bionic Leg

The device is a lightweight, wearable, portable, battery-powered, robotic leg orthosis that provides active assistance and resistance to lower limb movement according to the patient's intent to move.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Single ischemic stroke with residual unilateral lower-extremity weakness
* Chronic post-stroke (\>12 months since event)
* Eligible to participate to lower extremity physical therapy
* Age 30 years or greater
* Able to ambulate at least 10 meters without therapist assistance
* Able to ambulate without a leg brace
* Able to transfer from sitting to standing without physical assistance from a therapist
* Able to transfer from standing to sitting without physical assistance from a therapist
* Subject must understand the nature of the study and provide written informed consent prior to enrollment.
* Subject must be willing and able to attend all study sessions

Exclusion Criteria

* Medically unstable
* Age younger than 30 years
* Subacute post-stroke (\< 12 months since event)
* Status-post multiple strokes
* Status-post traumatic brain injury
* Not eligible to participate in lower extremity physical therapy
* Concomitant degenerative neurological conditions
* Not able to ambulate at least 10 meters without therapist assistance
* Unable to ambulate without a leg brace
* Unable to transfer from sitting to standing without physical assistance from a therapist
* Unable to transfer from standing to sitting without physical assistance from a therapist
* Unable to follow instructions, complete follow-up, or provide informed consent.
* Currently enrolled in another investigational device or drug trial
Minimum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of California, San Francisco

OTHER

Sponsor Role collaborator

Tibion Bionics, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Joshua G Vose, MD

Role: PRINCIPAL_INVESTIGATOR

Tibion Corporation

Locations

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UCSF Human Performance Center

San Francisco, California, United States

Site Status

Tibion Corporation

Sunnyvale, California, United States

Site Status

Countries

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United States

References

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Wong CK, Bishop L, Stein J. A wearable robotic knee orthosis for gait training: a case-series of hemiparetic stroke survivors. Prosthet Orthot Int. 2012 Mar;36(1):113-20. doi: 10.1177/0309364611428235. Epub 2011 Nov 14.

Reference Type BACKGROUND
PMID: 22082495 (View on PubMed)

Horst RW. A bio-robotic leg orthosis for rehabilitation and mobility enhancement. Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:5030-3. doi: 10.1109/IEMBS.2009.5333581.

Reference Type BACKGROUND
PMID: 19964374 (View on PubMed)

Horst RW, Marcus RR. FlexCVA: a continuously variable actuator for active orthotics. Conf Proc IEEE Eng Med Biol Soc. 2006;2006:2425-8. doi: 10.1109/IEMBS.2006.259950.

Reference Type BACKGROUND
PMID: 17946511 (View on PubMed)

Related Links

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http://www.Tibion.com

Tibion Bionic Leg

Other Identifiers

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CP 007

Identifier Type: -

Identifier Source: org_study_id