Trial Outcomes & Findings for Consumption of Potatoes, Avocados and Chickpeas and Cognitive Function in Older Adults (NCT NCT01620567)

NCT ID: NCT01620567

Last Updated: 2019-07-19

Results Overview

measures of sustained attention will be made using CANTAB, a sensitive computerized program. Signal detection measured on a scale from 0 to 1(bad to good).

• Recruitment status: COMPLETED
• Study phase: NA
• Target enrollment: 48 participants
• Primary outcome timeframe: 6 months
• Results posted on: 2019-07-19

Participant Flow

Participant milestones

Measure	Chickpeas/Potatoes 1 cup of chickpeas/potatoes for 6 months	Avocados 1 avocado/day for 6 months
Overall Study STARTED	23	25
Overall Study COMPLETED	20	20
Overall Study NOT COMPLETED	3	5

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Consumption of Potatoes, Avocados and Chickpeas and Cognitive Function in Older Adults

Baseline characteristics by cohort

Measure	Chickpeas/Potatoes n=20 Participants 1 cup chickpeas/potatoes for 6 months	Avocados n=20 Participants 1 avocado/day for 6 months	Total n=40 Participants Total of all reporting groups
Age, Categorical <=18 years	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Age, Categorical Between 18 and 65 years	15 Participants n=5 Participants	12 Participants n=7 Participants	27 Participants n=5 Participants
Age, Categorical >=65 years	5 Participants n=5 Participants	8 Participants n=7 Participants	13 Participants n=5 Participants
Sex: Female, Male Female	11 Participants n=5 Participants	13 Participants n=7 Participants	24 Participants n=5 Participants
Sex: Female, Male Male	9 Participants n=5 Participants	7 Participants n=7 Participants	16 Participants n=5 Participants
Race (NIH/OMB) American Indian or Alaska Native	1 Participants n=5 Participants	0 Participants n=7 Participants	1 Participants n=5 Participants
Race (NIH/OMB) Asian	0 Participants n=5 Participants	1 Participants n=7 Participants	1 Participants n=5 Participants
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) Black or African American	4 Participants n=5 Participants	5 Participants n=7 Participants	9 Participants n=5 Participants
Race (NIH/OMB) White	14 Participants n=5 Participants	13 Participants n=7 Participants	27 Participants n=5 Participants
Race (NIH/OMB) More than one race	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) Unknown or Not Reported	1 Participants n=5 Participants	1 Participants n=7 Participants	2 Participants n=5 Participants
Region of Enrollment United States	20 participants n=5 Participants	20 participants n=7 Participants	40 participants n=5 Participants

PRIMARY outcome

Timeframe: 6 months

measures of sustained attention will be made using CANTAB, a sensitive computerized program. Signal detection measured on a scale from 0 to 1(bad to good).

Outcome measures

Measure	Chickpeas/Potatoes n=20 Participants 1 potato/day or 1 cup chickpeas for 6 months	Avocados n=20 Participants 1 avocado/day for 6 months
Cognition baseline - rapid visual information processing	.90 units on a scale Standard Deviation .05	.86 units on a scale Standard Deviation .21
Cognition 3 mo - rapid visual information processing	.92 units on a scale Standard Deviation .05	.92 units on a scale Standard Deviation .04
Cognition 6 mo - rapid visual information processing	.92 units on a scale Standard Deviation .05	.93 units on a scale Standard Deviation .04

SECONDARY outcome

Timeframe: 0 months

C-reactive protein

Outcome measures

Measure	Chickpeas/Potatoes n=20 Participants 1 potato/day or 1 cup chickpeas for 6 months	Avocados n=20 Participants 1 avocado/day for 6 months
Inflammation	1.3 mg/L Standard Deviation 1.0	2.0 mg/L Standard Deviation 2.8

SECONDARY outcome

Timeframe: 3 month

C-reactive protein

Outcome measures

Measure	Chickpeas/Potatoes n=20 Participants 1 potato/day or 1 cup chickpeas for 6 months	Avocados n=20 Participants 1 avocado/day for 6 months
Inflammation	2.3 mg/L Standard Deviation 2.4	2.0 mg/L Standard Deviation 2.8

SECONDARY outcome

Timeframe: 6 month

C-reactive protein

Outcome measures

Measure	Chickpeas/Potatoes n=20 Participants 1 potato/day or 1 cup chickpeas for 6 months	Avocados n=20 Participants 1 avocado/day for 6 months
Inflammation	1.6 mg/L Standard Deviation 1.6	1.7 mg/L Standard Deviation 1.8

Adverse Events

Chickpeas/Potatoes

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Avocados

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Elizabeth J. Johnson, PhD

Tufts University

Phone: 617.556.3204

Email: elizabeth.johnson@tufts.edu

Results disclosure agreements

• Principal investigator is a sponsor employee
• Publication restrictions are in place