MITRAFIT- Cardinal Adjustable Mitral Repair Follow-up International Postmarketing Surveillance (PMS)

NCT ID: NCT01617720

Last Updated: 2021-11-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

45 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-05-31

Study Completion Date

2016-06-30

Brief Summary

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This Study is designed to observe the clinical outcomes of patients requiring mitral repair that were treated with the CE certified Cardinal System.

Detailed Description

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Conditions

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Mitral Regurgitation

Keywords

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mitral valve annuloplasty mitral regurgitation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age \> 18 years
* Patient is a candidate for mitral valve repair, with our without concomitant procedures.
* Subject is willing to give informed consent for collection of his/her clinical data.

Exclusion Criteria

* Severe organic lesions with retracted chordae
* Congenital malformations with lack of valvular tissue
* Severe valvular calcifications
* Evolving bacterial endocarditis
* Known Sensitivity to Nickel or Chromium
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Edwards Lifesciences

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ottavio Alfieri, Prof, MD

Role: PRINCIPAL_INVESTIGATOR

Hospital San Raffaele, Milan, Italy

Nicolas Doll, Prof, MD

Role: PRINCIPAL_INVESTIGATOR

SANA Herzchirurgie Stuttgart , Germany

Ehud Raanani, Prof, MD

Role: PRINCIPAL_INVESTIGATOR

Sheba Medical Center

Patrik Nataf, Prof, MD

Role: PRINCIPAL_INVESTIGATOR

Bichat Hospital, Paris, France

Volkmar Falk, Prof, MD

Role: PRINCIPAL_INVESTIGATOR

Zurich University, Zurich, Switzerland

Locations

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SANA Herzchirurgie

Stuttgart, , Germany

Site Status

Hospital San Rafaele

Milan, , Italy

Site Status

Countries

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Germany Italy

References

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Sundermann SH, Czesla M, Kempfert J, Walther T, Nataf P, Raanani E, Jacobs S, Alfieri O, Maisano F, Falk V. Results of mitral valve repair with an adjustable annuloplasty ring 2 years after implantation. Heart Vessels. 2017 Jul;32(7):843-849. doi: 10.1007/s00380-016-0934-7. Epub 2016 Dec 23.

Reference Type BACKGROUND
PMID: 28012074 (View on PubMed)

Other Identifiers

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VC1-2

Identifier Type: -

Identifier Source: org_study_id