Trial Outcomes & Findings for GlideScope®Video Laryngoscope for Difficult Intubation: Implication of the Size of Blade (NCT NCT01616771)

Results Overview

Glottis view was scored using C\&L grade by Macintosh laryngoscope and GVL selected by weight, and compared each other. We used modified C\&L grade: grade 1, all or most of the glottic aperture was visible; grade 2a, posterior cords and cartilage visible; grade 2b, only posterior cartilage visible; grade 3a, epiglottis visible and can be lifted; grade 3b, epiglottis adherent to the posterior pharynx; and grade 4, the epiglottis could not be visualized. For the statistical analysis, the modified C\&L grade was converted to an ordinal scale; grade 1 to 1, grade 2a to 2, grade 2b to 3, grade 3a to 4, grade 3b to 5, and grade 4 to 6. Therefore, score range for the data reported in the table was between 1 and 6, with 1 representing best view and 6 representing no view.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

23 participants

Primary outcome timeframe

up to 1 day of surgery

Results posted on

2014-11-04

Participant Flow

Participant milestones

Participant milestones
Measure	Glottis View Assessment After checking the C\&L grade using Macintosh laryngoscope, C\&L grade was re-evaluated using GVL selected by weight and smaller sized GVL in consecutive order.
Macintosh Laryngoscopy for 5 Sec STARTED	23
Macintosh Laryngoscopy for 5 Sec COMPLETED	23
Macintosh Laryngoscopy for 5 Sec NOT COMPLETED	0
GVL Selected by Weight for 5 Sec STARTED	23
GVL Selected by Weight for 5 Sec COMPLETED	23
GVL Selected by Weight for 5 Sec NOT COMPLETED	0
Smaller Sized GVL for 5 Sec STARTED	23
Smaller Sized GVL for 5 Sec COMPLETED	19
Smaller Sized GVL for 5 Sec NOT COMPLETED	4

Reasons for withdrawal

Reasons for withdrawal
Measure	Glottis View Assessment After checking the C\&L grade using Macintosh laryngoscope, C\&L grade was re-evaluated using GVL selected by weight and smaller sized GVL in consecutive order.
Smaller Sized GVL for 5 Sec lack of GVL size	4

Baseline Characteristics

GlideScope®Video Laryngoscope for Difficult Intubation: Implication of the Size of Blade

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Glottis View Assessment n=23 Participants After checking the C\&L grade using Macintosh laryngoscope, C\&L grade was re-evaluated using GVL selected by weight and smaller sized GVL in consecutive order.
Age, Categorical <=18 years	23 Participants n=5 Participants
Age, Categorical Between 18 and 65 years	0 Participants n=5 Participants
Age, Categorical >=65 years	0 Participants n=5 Participants
Age, Continuous	7.9 years STANDARD_DEVIATION 4.8 • n=5 Participants
Sex: Female, Male Female	10 Participants n=5 Participants
Sex: Female, Male Male	13 Participants n=5 Participants

PRIMARY outcome

Timeframe: up to 1 day of surgery

Glottis view was scored using C\&L grade by Macintosh laryngoscope and GVL selected by weight, and compared each other. We used modified C\&L grade: grade 1, all or most of the glottic aperture was visible; grade 2a, posterior cords and cartilage visible; grade 2b, only posterior cartilage visible; grade 3a, epiglottis visible and can be lifted; grade 3b, epiglottis adherent to the posterior pharynx; and grade 4, the epiglottis could not be visualized. For the statistical analysis, the modified C\&L grade was converted to an ordinal scale; grade 1 to 1, grade 2a to 2, grade 2b to 3, grade 3a to 4, grade 3b to 5, and grade 4 to 6. Therefore, score range for the data reported in the table was between 1 and 6, with 1 representing best view and 6 representing no view.

Outcome measures

Outcome measures
Measure	Macintosh Laryngoscope n=23 Participants After induction of anesthesia, Macintosh laryngoscope was inserted into mouth and C\&L grade was checked.	GVL Selected by Weight n=23 Participants Right after Macintosh laryngoscope was removed, C\&L grade was reassessed by second laryngoscopy, using GVL selected by weight.
The Differences in the Glottis View (C&L Grade) of Macintosh Laryngoscope and GVL Selected by Weight.	6 units on a scale Interval 5.5 to 6.0	5.5 units on a scale Interval 5.0 to 6.0

SECONDARY outcome

Timeframe: up to 1day of surgery

Population: Four of 23 patients could not be evaluated by smaller sized GVL because there was no smaller blade than their GVL selected by weight.

Glottis view was scored using C\&L grade by GVL selected by weight and smaller sized GVL, and compared each other. Score range for the data reported in the table was between 1 and 6, with 1 representing best view and 6 representing no view.

Outcome measures

Outcome measures
Measure	Macintosh Laryngoscope n=23 Participants After induction of anesthesia, Macintosh laryngoscope was inserted into mouth and C\&L grade was checked.	GVL Selected by Weight n=19 Participants Right after Macintosh laryngoscope was removed, C\&L grade was reassessed by second laryngoscopy, using GVL selected by weight.
The Differences in the Glottis View (C&L Grade) of GVL Selected by Weight and Smaller Sized GVL	5.5 units on a scale Interval 5.0 to 6.0	1 units on a scale Interval 1.0 to 1.5

Adverse Events

Macintosh Laryngoscope

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

GVL Selected by Weight

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Smaller Sized GVL

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Jin-Tae Kim

Seoul National University Hospital

Phone: 82-10-6260-8490

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place