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Lower Extremity Muscle and Function in the Elderly: Study 2

NCT ID: NCT01614392

Last Updated: 2018-12-10

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

52 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-09-30

Study Completion Date

2011-10-31

Brief Summary

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This research study is looking to compare the effects of two uniquely different power training interventions (high force, lower velocity versus low force, high velocity) on changes in mobility status among older individuals at risk for mobility disability.

Detailed Description

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Conditions

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Mobility Limitation

Keywords

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Resistance Exercise Physical Activity Mobility disability Physical function Muscle Strength Older Adults Mobility-Limited Peak power and strength

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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High velocity low force Power Training

Lower Extremity high velocity power training performed at lower external resistance (40% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).

Group Type EXPERIMENTAL

High velocity low force Power Training

Intervention Type BEHAVIORAL

Lower Extremity high velocity power training performed at lower external resistance (40% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).

Low velocity high force Power Training

Lower extremity low velocity power training performed at high external resistance (70% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).

Group Type EXPERIMENTAL

Low velocity high force Power Training

Intervention Type BEHAVIORAL

Lower extremity low velocity power training performed at high external resistance (70% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).

Interventions

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High velocity low force Power Training

Lower Extremity high velocity power training performed at lower external resistance (40% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).

Intervention Type BEHAVIORAL

Low velocity high force Power Training

Lower extremity low velocity power training performed at high external resistance (70% of the 1 repetition maximum muscle strength). Leg and knee extension exercises were performed twice per week (3 sets of each exercise consisting of 10 repetitions).

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Male and Female 70-85 yrs
* Community dwelling
* Short Performance Battery Score \>9
* BMI range 19-32 kg/m2
* Willingness to be randomized and come the laboratory for 20 weeks.

Exclusion Criteria

* Acute or Terminal Illness
* MI in previous 6 months, symptomatic coronary artery disease or congestive heart failure.
* Upper or Lower extremity fracture in previous 6 months
* Uncontrolled hypertension (150/90mmHg)
* Neuromuscular diseases and drugs that affect neuromuscular function
* Hormone replacement therapy
* Participation in any regular endurance or resistance training exercise during previous 3 months
Minimum Eligible Age

70 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Tufts University

OTHER

Sponsor Role lead

Responsible Party

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Roger A Fielding

Director and Senior Scientist, Professor of Nutrition, Jean Mayer USDA Human Nutrition Research Center on Aging.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Roger A Fieilding, Ph D.

Role: PRINCIPAL_INVESTIGATOR

Jean Mayer USDA Human Nutrition Research Center on Aging

Locations

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Jean Mayer USDA Human Nutrition Research Center on Aging

Boston, Massachusetts, United States

Site Status

Countries

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United States

Other Identifiers

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AG-18844

Identifier Type: -

Identifier Source: org_study_id