Trial Outcomes & Findings for Lumbar Punctures in Neonates: Improving Success Rates and Minimizing Pain (NCT NCT01606150)

NCT ID: NCT01606150

Last Updated: 2016-12-13

Results Overview

Success defined as cerebrospinal fluid for a culture and red blood cell count less than 1000

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

5 participants

Primary outcome timeframe

immediately following the procedure

Results posted on

2016-12-13

Participant Flow

Participant milestones

Participant milestones
Measure
Subcutaneous Lidocaine
0.1 ml/kg of 1% Lidocaine 1% lidocaine: 0.1 ml/kg of 1% lidocaine injected over lumbar puncture needle insertion site 2 minutes prior to procedure
Topical Lidocaine
LMX-4, 1 gram placed over lumbar puncture needle insertion site 30 minutes prior to the procedure topical lidocaine: 1 gram placed over lumbar puncture needle insertion point 30 minutes prior to procedure
Overall Study
STARTED
0
0
Overall Study
COMPLETED
0
0
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Lumbar Punctures in Neonates: Improving Success Rates and Minimizing Pain

Baseline characteristics by cohort

Baseline data not reported

PRIMARY outcome

Timeframe: immediately following the procedure

Success defined as cerebrospinal fluid for a culture and red blood cell count less than 1000

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: data collected during the procedure, PIPP score assigned within one month by viewing collected data

PIPP score assigned by a blinded outcome assessor by viewing video tapes of the infant's face during the procedure and vital sign changes during that time frame

Outcome measures

Outcome data not reported

Adverse Events

Subcutaneous Lidocaine

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Topical Lidocaine

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Judith Palafoutas, Research Director

Georgetown University NICU

Phone: 202 444 8756

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place