Trial Outcomes & Findings for Twitter-enabled Mobile Messaging for Smoking Relapse Prevention (NCT NCT01602536)

Results Overview

self-reported 7-day point prevalence abstinence from smoking that was sustained at 60 days after the quit date, based on survey

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

160 participants

Primary outcome timeframe

60 days after quit date

Results posted on

2024-10-31

Participant Flow

Participant milestones

Participant milestones
Measure	Twitter Experimental participants are assigned a 20-person twitter quit-smoking group to interact with, are instructed to use Twitter-enabled interactive peer messaging,and are sent daily messages to encourage interaction. The baseline intervention 'smoking cessation aides' is also provided. smoking cessation aides: All participants will receive 8 weeks of free nicotine patches, referral to the NCI's online Smokefree.gov Quit Guide, and instruction to set a quit date within 8 days of study start. Twitter: Twitter quit-smoking group	Control Control participants are not assigned to a twitter group. The baseline intervention 'smoking cessation aides' is also provided. smoking cessation aides: All participants will receive 8 weeks of free nicotine patches, referral to the NCI's online Smokefree.gov Quit Guide, and instruction to set a quit date within 8 days of study start.
Overall Study STARTED	80	80
Overall Study COMPLETED	65	70
Overall Study NOT COMPLETED	15	10

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Twitter-enabled Mobile Messaging for Smoking Relapse Prevention

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Twitter n=80 Participants Experimental participants are assigned a 20-person twitter quit-smoking group to interact with, are instructed to use Twitter-enabled interactive peer messaging,and are sent daily messages to encourage interaction. The baseline intervention 'smoking cessation aides' is also provided. smoking cessation aides: All participants will receive 8 weeks of free nicotine patches, referral to the NCI's online Smokefree.gov Quit Guide, and instruction to set a quit date within 8 days of study start. Twitter: Twitter quit-smoking group	Control n=80 Participants Control participants are not assigned to a twitter group. The baseline intervention 'smoking cessation aides' is also provided. smoking cessation aides: All participants will receive 8 weeks of free nicotine patches, referral to the NCI's online Smokefree.gov Quit Guide, and instruction to set a quit date within 8 days of study start.	Total n=160 Participants Total of all reporting groups
Age, Continuous age	35.35 years STANDARD_DEVIATION 10.55 • n=5 Participants	36.00 years STANDARD_DEVIATION 9.16 • n=7 Participants	35.68 years STANDARD_DEVIATION 9.85 • n=5 Participants
Sex: Female, Male Female	55 Participants n=5 Participants	61 Participants n=7 Participants	116 Participants n=5 Participants
Sex: Female, Male Male	25 Participants n=5 Participants	19 Participants n=7 Participants	44 Participants n=5 Participants

PRIMARY outcome

Timeframe: 60 days after quit date

self-reported 7-day point prevalence abstinence from smoking that was sustained at 60 days after the quit date, based on survey

Outcome measures

Outcome measures
Measure	Twitter n=65 Participants Experimental participants are assigned a 20-person twitter quit-smoking group to interact with, are instructed to use Twitter-enabled interactive peer messaging,and are sent daily messages to encourage interaction. The baseline intervention 'smoking cessation aides' is also provided. smoking cessation aides: All participants will receive 8 weeks of free nicotine patches, referral to the NCI's online Smokefree.gov Quit Guide, and instruction to set a quit date within 8 days of study start. Twitter: Twitter quit-smoking group	Control n=70 Participants Control participants are not assigned to a twitter group. The baseline intervention 'smoking cessation aides' is also provided. smoking cessation aides: All participants will receive 8 weeks of free nicotine patches, referral to the NCI's online Smokefree.gov Quit Guide, and instruction to set a quit date within 8 days of study start.
Self-reported 7-day Point Prevalence Abstinence From Smoking That Was Sustained at 60 Days After the Quit Date	26 Participants	14 Participants

SECONDARY outcome

Timeframe: 100 days total

Population: all participants were observed to assess their tweeting (posting) behavior

level of engagement based on tweet volume which is observed in support groups

Outcome measures

Outcome measures
Measure	Twitter n=80 Participants Experimental participants are assigned a 20-person twitter quit-smoking group to interact with, are instructed to use Twitter-enabled interactive peer messaging,and are sent daily messages to encourage interaction. The baseline intervention 'smoking cessation aides' is also provided. smoking cessation aides: All participants will receive 8 weeks of free nicotine patches, referral to the NCI's online Smokefree.gov Quit Guide, and instruction to set a quit date within 8 days of study start. Twitter: Twitter quit-smoking group	Control n=80 Participants Control participants are not assigned to a twitter group. The baseline intervention 'smoking cessation aides' is also provided. smoking cessation aides: All participants will receive 8 weeks of free nicotine patches, referral to the NCI's online Smokefree.gov Quit Guide, and instruction to set a quit date within 8 days of study start.
Level of Engagement Based on Tweet Volume	58.86 social media posts Standard Deviation 68.02	0 social media posts Standard Deviation 0

Adverse Events

Twitter

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Control

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Cornelia Pechmann

University of California, Irvine

Phone: 310-892-0619

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place