Trial Outcomes & Findings for Post Photorefractive Keratectomy (PRK) Use of an Eye Shield for Maintaining Vision and Mitigating Pain (NCT NCT01592643)

NCT ID: NCT01592643

Last Updated: 2021-12-22

Results Overview

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

30 participants

Primary outcome timeframe

Day 30

Results posted on

2021-12-22

Participant Flow

Unit of analysis: Eyes

Participant milestones

Participant milestones
Measure
Eye Shield
Participants receive eye shield during PRK surgery Eye Shield: The thin shield is made of silicone. The materials used to make the corneal shield all have a history of use in medical devices, contact lenses, and/or corneal shields and have been used safely in the eye.
Overall Study
STARTED
30 45
Overall Study
COMPLETED
30 45
Overall Study
NOT COMPLETED
0 0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Post Photorefractive Keratectomy (PRK) Use of an Eye Shield for Maintaining Vision and Mitigating Pain

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Eye Shield
n=45 Eyes
Participants receive eye shield during PRK surgery
Age, Continuous
38.6 years
STANDARD_DEVIATION 8.6 • n=5 Participants
Sex: Female, Male
Female
14 Participants
n=5 Participants
Sex: Female, Male
Male
16 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
2 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
27 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
1 Participants
n=5 Participants
Region of Enrollment
United States
30 Participants
n=5 Participants

PRIMARY outcome

Timeframe: Day 30

Outcome measures

Outcome measures
Measure
Eye Shield
n=30 Participants
Participants receive eye shield during PRK surgery
Number of Participants With Pain Score of Four or Greater. Score Range: 0-10, Higher Score Corresponds to More Pain.
0 Participants

SECONDARY outcome

Timeframe: Six months

LogMAR uncorrected visual acuity. Values closer to zero indicate improved vision

Outcome measures

Outcome measures
Measure
Eye Shield
n=45 Eyes
Participants receive eye shield during PRK surgery
Mean Change in Uncorrected Visual Acuity
Baseline
1.34 logMAR
Standard Deviation 0.55
Mean Change in Uncorrected Visual Acuity
Month six
-0.06 logMAR
Standard Deviation 0.11

Adverse Events

Eye Shield

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Edward E. Manche

Stanford University School of Medcine

Phone: 6507255765

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place