MedDataX Logo

Caffeine and Sodium Citrate Ingestion

NCT ID: NCT01591226

Last Updated: 2016-11-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

9 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-02-29

Study Completion Date

2012-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

A positive ergogenic effect of sodium citrate and caffeine ingestion in a short-term, high-intensity exercise task was shown by several studies. These studies were conducted with healthy, able-bodied subjects.

The aim of the study is to investigate whether caffeine or sodium citrate ingestion could enhance performance in spinal cord injured wheelchair athletes. It is a double blind, placebo controlled and randomized study.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The athletes have to complete four 1500m tests on a training roller. Before each treatment they get different supplementations. Once they get sodium citrate and a placebo, once caffeine and a placebo, once sodium citrate and caffeine and for the fourth treatment they get twice a placebo. Two hours after starting with the supplementation they have to complete the 1500m as fast as possible. Time to complete 1500m, blood pH, plasma bicarbonate, sodium concentration, heart rate, oxygen consumption, blood lactate concentration and rate of perceived exertion (RPE) were measured.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Dietary Supplements Heart Rate/Drug Effects Lactic Acid/Metabolism Physical Education and Training/Methods Wheelchairs

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

caffeine sodium citrate exercise performance wheelchair athletes 1500m

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Caffeine

6mg per kg bodyweight ingested 60min before test

Group Type ACTIVE_COMPARATOR

Caffeine

Intervention Type DIETARY_SUPPLEMENT

gelatine capsule 6mg/kg bodyweight 60min prior test

Sodium Chloride

Intervention Type DIETARY_SUPPLEMENT

sodium chloride diluted in 7dl water 0.045g/kg bodyweight 120-90min prior test

Placebo

Sodium chloride and mannitol as placebo are ingested by the athlete

Group Type PLACEBO_COMPARATOR

Mannitol

Intervention Type DIETARY_SUPPLEMENT

gelatine capsule filled with mannitol (100mg per capsule) ingested 60min prior test

Sodium Chloride

Intervention Type DIETARY_SUPPLEMENT

sodium chloride diluted in 7dl water 0.045g/kg bodyweight 120-90min prior test

Sodium Citrate

sodium citrate diluted in 7dl water, ingestion 120 to 90min prior test

Group Type ACTIVE_COMPARATOR

Sodium Citrate

Intervention Type DIETARY_SUPPLEMENT

0.5g/kg bodyweight diluted in 7dl water ingested 120-90min prior test

Mannitol

Intervention Type DIETARY_SUPPLEMENT

gelatine capsule filled with mannitol (100mg per capsule) ingested 60min prior test

Caffeine and Sodium Citrate

sodium citrate 120-90min prior test capsules:60min prior test

Group Type ACTIVE_COMPARATOR

Caffeine

Intervention Type DIETARY_SUPPLEMENT

gelatine capsule 6mg/kg bodyweight 60min prior test

Sodium Citrate

Intervention Type DIETARY_SUPPLEMENT

0.5g/kg bodyweight diluted in 7dl water ingested 120-90min prior test

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Caffeine

gelatine capsule 6mg/kg bodyweight 60min prior test

Intervention Type DIETARY_SUPPLEMENT

Sodium Citrate

0.5g/kg bodyweight diluted in 7dl water ingested 120-90min prior test

Intervention Type DIETARY_SUPPLEMENT

Mannitol

gelatine capsule filled with mannitol (100mg per capsule) ingested 60min prior test

Intervention Type DIETARY_SUPPLEMENT

Sodium Chloride

sodium chloride diluted in 7dl water 0.045g/kg bodyweight 120-90min prior test

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* wheelchair athletes
* national team
* category T53 and T54

Exclusion Criteria

* medicated
* pregnant (for women)
* cardiovascular and respiratory diseases
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Swiss Paraplegic Research, Nottwil

NETWORK

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Claudio Perret, Dr. sc. nat.

Role: PRINCIPAL_INVESTIGATOR

Swiss Paraplegic Research, Nottwil

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Swiss Paraplegic Centre

Nottwil, Canton of Lucerne, Switzerland

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Switzerland

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2012-02

Identifier Type: -

Identifier Source: org_study_id