The Effects of Escitalopram on Cytokines

NCT ID: NCT01587326

Last Updated: 2012-05-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

25 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-04-30

Study Completion Date

2013-04-30

Brief Summary

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The association of cytokines with escitalopram has not been investigated in patients with major depressive disorder (MDD). Hence, the investigators will examine this association.

Detailed Description

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In addition to serotonin, inflammatory process has been suggested in the development of major depressive disorder (MDD) and in its associated treatment. Escitalopram is an antidepressant that has been widely used in patients with MDD because of the promising results. The association of cytokines with escitalopram has not been investigated in patients with MDD. Hence, the investigators will examine this association.

Conditions

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Depression

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Escitalopram

Escitalopram 10 mg/d to 20 mg/d

Group Type EXPERIMENTAL

Escitalopram

Intervention Type DRUG

escitalopram 10 mg/d to 20 mg/d

Interventions

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Escitalopram

escitalopram 10 mg/d to 20 mg/d

Intervention Type DRUG

Other Intervention Names

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Lexapro

Eligibility Criteria

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Inclusion Criteria

1. DSM-IV-defined Major depressive disorder, single episode
2. Age 20-65
3. Drug-naive
4. Hamilton Depression Rating Scale exceeding 14 scores

Exclusion Criteria

1. Major medical disorders
2. Substance use
3. Pregnant
4. Allergy to escitalopram
Minimum Eligible Age

20 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Beitou Armed Forces Hospital, Taipei, Taiwan

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Peishen Ho, M.D.

Role: STUDY_CHAIR

Beitou Armed Forces Hospital

Locations

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Beitou Armed Forces Hospital

Taipei, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Pei-Shen Ho, M.D.

Role: CONTACT

+886-2-28959808

Facility Contacts

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Chih-Sung Liang, M.D.

Role: primary

+886-2-8959808

Other Identifiers

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BAFH

Identifier Type: OTHER

Identifier Source: secondary_id

BAFH-101-05

Identifier Type: -

Identifier Source: org_study_id

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