A Study to Evaluate Two Different Surgical Methods for Treatment for Abdominal Wall Diastasis

NCT ID: NCT01586741

Last Updated: 2020-12-23

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

96 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-12-31

Study Completion Date

2012-12-31

Brief Summary

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This is a three armed prospective randomized trial that will compare two different surgical techniques for reconstruction of the abdominal wall diastasis with a conservative treatment procedure.

The study hypothesis:

Which surgical approach provides the safest and best long term results for patients with abdominal wall diastasis either the insertion of net alternative with a double row suture or exercise alone?

Detailed Description

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The conservative control group will receive a special training program for abdominal muscle training for 3 months,and all groups wearing girdle for 3 months.

All patients examined with a CT scan before randomization and then a Biodex measurement of abdominal muscle strength.

All patients must also complete the SF-36 (scientifically tested instruments to measure self-reported physical and mental health) and VHPQ (ventral hernia Pain Questionnaire).

Two-thirds of patients receive surgery and followed up with a 3 month and 1-year control.At 1 year of control, all go through a CT scan and a Biodex measurement of muscle strength.

The control group followed up after one and half months and 3 months. In the surgery group, patients may not know what reconstruction they received before the final assessment after 1 year.

Conditions

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Abdominal Hernias and Other Abdominal Wall Conditions Post-operative Pain Recurrence

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Polypropylene mesh

Reconstruction of the abdominal wall diastasis with insertion of a polypropylene mesh on 30 patients.

Group Type ACTIVE_COMPARATOR

Quill suture application for repair or polypropylene mesh

Intervention Type PROCEDURE

The first arm may be insertion of the-mesh The second arm may double row- suture The third arm may be conservative -training

quill suture

Reconstruction of the abdominal wall diastasis with double row absorbable suture ( Quill Self-retaining system) on 30 patients.

Group Type ACTIVE_COMPARATOR

Quill suture application for repair or polypropylene mesh

Intervention Type PROCEDURE

The first arm may be insertion of the-mesh The second arm may double row- suture The third arm may be conservative -training

conservative treatment

Regular abdominal exercises workout for three months for 30 patients.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Quill suture application for repair or polypropylene mesh

The first arm may be insertion of the-mesh The second arm may double row- suture The third arm may be conservative -training

Intervention Type PROCEDURE

Other Intervention Names

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Quill suture And Soft mesh Polypropylene mesh

Eligibility Criteria

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Inclusion Criteria

1. Abdominal wall diastasis\> 3 cm
2. Discomfort or tenderness in the abdominal wall
3. Desire for abdominal wall reconstruction
4. Women have undergone at least one birth
5. Smoking cessation 1 month pre-and 3 months post-operatively

Exclusion Criteria

1. \<18 years old
2. Ongoing pregnancy
3. Ongoing breastfeeding
4. Current immunosuppressive therapy
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Karolinska Institutet

OTHER

Sponsor Role lead

Responsible Party

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Peter Emanuelsson

MD, consultant in plastic surgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ulf S Gunnarsson, professor

Role: STUDY_DIRECTOR

Karolinska Institutet

Locations

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Clintec, Karolinska Institutet

Stockholm, , Sweden

Site Status

Countries

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Sweden

References

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Emanuelsson P, Gunnarsson U, Strigard K, Stark B. Early complications, pain, and quality of life after reconstructive surgery for abdominal rectus muscle diastasis: a 3-month follow-up. J Plast Reconstr Aesthet Surg. 2014 Aug;67(8):1082-8. doi: 10.1016/j.bjps.2014.04.015. Epub 2014 May 2.

Reference Type DERIVED
PMID: 24880577 (View on PubMed)

Other Identifiers

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2009/227-31/3/PE/96

Identifier Type: -

Identifier Source: org_study_id