Trial Outcomes & Findings for B-type Natriuretic Peptide as a Surrogate Marker Guiding Post-operative Fluid Off-loading (NCT NCT01584518)

Results Overview

The subjects will be evaluated preoperatively and followed post-operatively until discharge from the hospital. Length of stay

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

50 participants

Primary outcome timeframe

From date of admission until date of discharge, assessed up to 1 month

Results posted on

2016-05-27

Participant milestones
Measure	CHF Peptide Diuresis based on CHF-P Furosemide: Based on clinical standard per clinician	Non CHF Peptide Diuresis based on clinical judgement without data for CHF-P
Overall Study STARTED	25	25
Overall Study COMPLETED	25	25
Overall Study NOT COMPLETED	0	0

Withdrawal data not reported

B-type Natriuretic Peptide as a Surrogate Marker Guiding Post-operative Fluid Off-loading

Baseline characteristics by cohort
Measure	CHF Peptide n=25 Participants Diuresis based on CHF-P Furosemide: Based on clinical standard per clinician	Non CHF Peptide n=25 Participants Diuresis based on clinical judgement without data for CHF-P	Total n=50 Participants Total of all reporting groups
Age, Continuous	70 years STANDARD_DEVIATION 10 • n=5 Participants	70 years STANDARD_DEVIATION 9 • n=7 Participants	70 years STANDARD_DEVIATION 9.5 • n=5 Participants
Sex: Female, Male Female	6 Participants n=5 Participants	7 Participants n=7 Participants	13 Participants n=5 Participants
Sex: Female, Male Male	19 Participants n=5 Participants	18 Participants n=7 Participants	37 Participants n=5 Participants

Timeframe: From date of admission until date of discharge, assessed up to 1 month

The subjects will be evaluated preoperatively and followed post-operatively until discharge from the hospital. Length of stay

Outcome measures
Measure	CHF Peptide n=25 Participants Diuresis based on CHF-P Furosemide: Based on clinical standard per clinician	Non CHF Peptide n=25 Participants Diuresis based on clinical judgement without data for CHF-P
Length of Stay	4 days Standard Deviation 3	6 days Standard Deviation 5

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious events: 4 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events
Measure	CHF Peptide n=25 participants at risk Diuresis based on CHF-P Furosemide: Based on clinical standard per clinician	Non CHF Peptide n=25 participants at risk Diuresis based on clinical judgement without data for CHF-P
Renal and urinary disorders Acute renal failure	0.00% 0/25 • 8 months	8.0% 2/25 • Number of events 2 • 8 months
Cardiac disorders Death	0.00% 0/25 • 8 months	8.0% 2/25 • Number of events 2 • 8 months

Adverse event data not reported

Creighton University

Phone: 402-280-3586