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Obstructive Sleep Apnea in Pulmonary Embolism

NCT ID: NCT01580085

Last Updated: 2012-04-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

75 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-11-30

Study Completion Date

2010-12-31

Brief Summary

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Obstructive sleep apnea (OSA) is a clinical syndrome characterized by repetitive closure of the airway and frequent awakenings during sleep. Repeated episodes of hypoxia, decrease in intrathoracic pressure, increased venous return and venous stasis, damage to vascular wall may ensue. An increased tendency for coagulation has also been reported in OSA. Venous stasis, vascular endothelial activation and hypercoagulability are also known risk factors for thromboembolism. All of these pathophysiologic changes in OSA may predispose patients for the development of pulmonary embolism (PE) however there is limited data about role of thromboembolic events in OSA.

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Detailed Description

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Conditions

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Pulmonary Thromboembolism Obstructive Sleep Apnea

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Pulmonary embolism

Patients who were diagnosed with pulmonary embolism

polysomnography

Intervention Type OTHER

full night supervised laboratory polysomnography

control group

age and sex matched adults with osa and no thromboembolism

polysomnography

Intervention Type OTHER

full night supervised laboratory polysomnography

Interventions

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polysomnography

full night supervised laboratory polysomnography

Intervention Type OTHER

Other Intervention Names

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PSG

Eligibility Criteria

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Inclusion Criteria

* All consecutive patients diagnosed with pulmonary embolism

Exclusion Criteria

* less than 18 years of age
* any restrictive or obstructive lung disease
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Gaziantep

OTHER

Sponsor Role lead

Responsible Party

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meral uyar

Asisstant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Meral Uyar, Assist Prof

Role: PRINCIPAL_INVESTIGATOR

University of Gaziantep

Locations

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University of Gaziantep Hospital

Gaziantep, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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gantep gogus 1

Identifier Type: -

Identifier Source: org_study_id

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