Trial Outcomes & Findings for Hair2Go Label Comprehension and Usability Study (NCT NCT01578187)

NCT ID: NCT01578187

Last Updated: 2013-12-25

Results Overview

Label comprehension will be based on responses to a questionnaire. Questions will be based on a tiered system by level of importance in responding correctly according to the following: 1. Questions regarding safe use of the system. 2. Questions regarding correct use of the system(not related to safety). In order to demonstrate how well the label instruction, as a whole, was understood by all subjects, the proportion of subjects who correctly understood the label as a whole was calculated by classifying each subject as either a "responder" or "non-responder" based on the following criteria regarding all questions: A subject was considered a responder if he/she correctly answered 11/12 questions related to safety AND 5/6 low category questions not related to safety. The study was considered a success if the response rate (i.e., the proportion of subjects correctly understanding the label based on the responder criteria) was at least 90%.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

63 participants

Primary outcome timeframe

1 hour

Results posted on

2013-12-25

Participant Flow

The study was conducted at a single site specialized in consumer product testing.

Participant milestones

Participant milestones
Measure
Hair2Go Device
This group included subjects who participated in the label comprehension phase. From these subjects, 48 subjects self-included in the usability phase (no contraindications) and chose to use the device for 1 treatment. The subjects included all skin types and a population of low health literacy subjects based on the Rapid Estimate of Adult Literacy in Medicine (REALM) test.
Label Comprehension Phase
STARTED
63
Label Comprehension Phase
COMPLETED
63
Label Comprehension Phase
NOT COMPLETED
0
Usability Phase
STARTED
48
Usability Phase
COMPLETED
47
Usability Phase
NOT COMPLETED
1

Reasons for withdrawal

Reasons for withdrawal
Measure
Hair2Go Device
This group included subjects who participated in the label comprehension phase. From these subjects, 48 subjects self-included in the usability phase (no contraindications) and chose to use the device for 1 treatment. The subjects included all skin types and a population of low health literacy subjects based on the Rapid Estimate of Adult Literacy in Medicine (REALM) test.
Usability Phase
Withdrawal by Subject
1

Baseline Characteristics

Hair2Go Label Comprehension and Usability Study

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Hair2Go Device
n=63 Participants
The subjects who participated in the label comprehension phase, of them most participated in the usability phase. The subjects included all skin types and a population of low health literacy subjects based on the Rapid Estimate of Adult Literacy in Medicine (REALM)test.
Age, Categorical
<=18 years
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
63 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
Age, Continuous
42 years
STANDARD_DEVIATION 13 • n=5 Participants
Sex: Female, Male
Female
46 Participants
n=5 Participants
Sex: Female, Male
Male
17 Participants
n=5 Participants
Region of Enrollment
United States
63 participants
n=5 Participants

PRIMARY outcome

Timeframe: 1 hour

Population: Sample size was discussed with the FDA during a pre-IDE teleconference

Label comprehension will be based on responses to a questionnaire. Questions will be based on a tiered system by level of importance in responding correctly according to the following: 1. Questions regarding safe use of the system. 2. Questions regarding correct use of the system(not related to safety). In order to demonstrate how well the label instruction, as a whole, was understood by all subjects, the proportion of subjects who correctly understood the label as a whole was calculated by classifying each subject as either a "responder" or "non-responder" based on the following criteria regarding all questions: A subject was considered a responder if he/she correctly answered 11/12 questions related to safety AND 5/6 low category questions not related to safety. The study was considered a success if the response rate (i.e., the proportion of subjects correctly understanding the label based on the responder criteria) was at least 90%.

Outcome measures

Outcome measures
Measure
Label Comprehension Group
n=63 Participants
Subjects that participated in the label comprehension phase of the study
Usability - Non Critical Error
Non critical error: An error that, if repeated without correction/intervention, may cause an adverse event.
Percent of Participants Correctly Determining Eligibility for Use of the Device (Responders)
94 percentage of participants

PRIMARY outcome

Timeframe: 1-2 hours

Population: Subjects who were not self-excluders in the label comprehension phase and consented to continue to the usability phase (product use).

Study staff will record the number of errors according to the following: 1. Critical error: an error that may cause a serious adverse event or an adverse event from a single occurrence 2. Non critical error: An error that, if repeated without correction/intervention, may cause an adverse event.

Outcome measures

Outcome measures
Measure
Label Comprehension Group
n=47 Participants
Subjects that participated in the label comprehension phase of the study
Usability - Non Critical Error
n=47 Participants
Non critical error: An error that, if repeated without correction/intervention, may cause an adverse event.
Percentage of Participants Performing Critical/Non-critical Errors
0 percentage of participants with errors
2.1 percentage of participants with errors

Adverse Events

Hair2Go (Me) Device

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Doran Rozen, Director of Clinical Affairs

Syneron Beauty

Phone: +972-54-7800260

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place