Comparison of Open Versus Masked Distal EtCO2 Monitoring of Neonates Ventilated With Conventional Ventilation

NCT ID: NCT01572272

Last Updated: 2016-11-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

66 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-08-31

Study Completion Date

2015-02-28

Brief Summary

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Primary:

The purpose of this study is to assess the clinical implications of continuous distal CO2 monitoring when used for clinical decisions

Sub Study:

• Evaluate the average life time (duration) of Standard Carinal VitaLine set in comparison to the Carinal VitaLine set that its sampling tubing is made of PEBAX (dehumidifying material).

Description of Study Design:

Patients will be randomized at the baseline evaluation visit into one of the following groups:

* Masked group: Data derived from the Capnostream20p will be recorded; however the medical staff will be masked from it and hence will not use it.
* Open group: Data derived from the Capnostream20p and displayed to the medical team. It will allow the treating physician and the nursing team to review the real time data and make clinical decisions based upon it if felt necessary.

Detailed Description

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Conditions

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Intubated Neonates That Require Conventional Ventilation

Keywords

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Distal Capnography CO2 neonates conventional ventilation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Open

Open group: Data derived from the Capnostream20p and displayed to the medical team. It will allow the treating physician and the nursing team to review the real time data and make clinical decisions based upon it if felt necessary.

No interventions assigned to this group

Masked

Data derived from the Capnostream20p will be recorded; however the medical staff will be masked from it and hence will not use it.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Intubated neonates with double-lumen ETT (Uncuffed Tracheal Tube, Mallinckrodt Inc., Chih, Mexico) that their respiratory condition requires conventional ventilation.
* Obtaining signed Informed Consent Form by the parents or legal guardian
* Intubated neonates that are expected to provide at least 3 pairs of blood samples and ETCO2 measurements during ventilation period

Exclusion Criteria

* Intubated neonates with single-lumen ETTs
* Neonates who are ventilated with HFV
* Any significant medical condition which, at the investigator's discretion, may interfere with the study.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Oridion

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Amir Kugelman, Prof.

Role: PRINCIPAL_INVESTIGATOR

Bnai Zion MC, Haifa Israel

Locations

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Soroka MC

Beersheba, , Israel

Site Status

Bnai Zion MC

Haifa, , Israel

Site Status

Shaare Zedek MC

Jerusalem, , Israel

Site Status

Countries

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Israel

References

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Kugelman A, Golan A, Riskin A, Shoris I, Ronen M, Qumqam N, Bader D, Bromiker R. Impact of Continuous Capnography in Ventilated Neonates: A Randomized, Multicenter Study. J Pediatr. 2016 Jan;168:56-61.e2. doi: 10.1016/j.jpeds.2015.09.051. Epub 2015 Oct 17.

Reference Type DERIVED
PMID: 26490126 (View on PubMed)

Other Identifiers

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D007157

Identifier Type: -

Identifier Source: org_study_id