Narrowband UVB for Children With Moderate to Severe Atopic Eczema

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

58 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-04-30

Study Completion Date

2010-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

To assess prospectively, the response of moderate to severe atopic eczema to a standard course of narrowband ultraviolet B phototherapy by using validated objective and subjective scoring systems.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Narrowband Ultraviolet B Versus Narrowband Ultraviolet B Plus Ultraviolet A1 for Atopic Eczema

NCT02915146

Atopic Eczema

COMPLETED NA

Narrow-band (NB)-UVB vs. Bath-PUVA and NB-UVB Plus Salt Water Baths in Atopic Dermatitis

NCT01402414

Atopic Dermatitis

TERMINATED NA

BROadband vs Narrowband photoTherapy for Eczema Trial Nested in the CACTI Cohort

NCT04818138

Atopic Dermatitis Skin Diseases Eczema

TERMINATED NA

Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis

NCT00533195

Atopic Dermatitis

COMPLETED PHASE3

Topical PDT Cream Without Irradiation Source in the Acne Treatment

NCT02313467

Acne, Photodynamic Therapy

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Children with moderate to severe atopic eczema prescribed a course of narrowband UVB phototherapy were scored (using validated scoring systems) objectively and subjectively before, during and after the course of treatment, as well as 3 and 6 months post treatment (to determine length of remission). Their scores were compared to a control group. The control group comprised children with moderate to severe atopic eczema who were offered UVB but were unable to undertake the treatment.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Moderate to Severe Atopic Eczema

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

UVB

Children with moderate to severe atopic eczema who undertook a standard course of narrowband Ultraviolet B (NBUVB) phototherapy

Narrowband Ultraviolet B phototherapy

Intervention Type RADIATION

Twice weekly exposures for a total of 24 exposures using a standard phototherapy protocol.

Controls

Children with moderate to severe atopic eczema who were offered UVB but were unable to undertake treatment

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Narrowband Ultraviolet B phototherapy

Twice weekly exposures for a total of 24 exposures using a standard phototherapy protocol.

Intervention Type RADIATION

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Children aged 3-16 years with moderate to severe atopic eczema (as defined by the modified Hannifin and Rajka criteria) in whom there is a clinical indication for phototherapy (as deemed by their specialist Dermatology consultant).

Exclusion Criteria

* Children under the age of 3 years or any child who lacks the maturity needed to stand in the phototherapy cabinet unsupervised.
* Mild disease (defined as a Six Area Six Sign Atopic Dermatitis (SASSAD) score \<10)

Minimum Eligible Age

3 Years

Maximum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No