Assessment of PCSO-524 Relative to a Comparator Product

NCT ID: NCT01564160

Last Updated: 2012-12-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

EARLY_PHASE1

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-04-30

Study Completion Date

2012-08-31

Brief Summary

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A marine lipid oil extract isolated from the New Zealand Greenshell® Mussel, Perna canaliculus (P. canaliculus), contains a unique synergistic blend of marine fatty acids.

The objective of the this study is to evaluate the acute (5-hour) and chronic (21-day) bioavailability of a fixed dose of PCSO-524 compared to a fish oil product in a population of healthy adult participants.

Detailed Description

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Conditions

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Healthy

Keywords

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Fish Oil EPA DHA Omega-Score Omega-3 Fatty Acids Green-Lipped Mussel Omega-score < 5.2%

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Arm 1: PCSO-524

PCSO-524

Group Type EXPERIMENTAL

PCSO-524

Intervention Type DIETARY_SUPPLEMENT

Extract of Greenshell Mussel

Arm 2: Fish Oil

Fish Oil

Group Type ACTIVE_COMPARATOR

Fish Oil

Intervention Type DIETARY_SUPPLEMENT

Source of omega-3 fatty acids.

Interventions

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Fish Oil

Source of omega-3 fatty acids.

Intervention Type DIETARY_SUPPLEMENT

PCSO-524

Extract of Greenshell Mussel

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* The individual is fluent in English and understands the study requirements
* The participant is willing and able to comply with all requirements defined within this protocol.
* The individual is willing to provide written informed consent
* The individual is male or female
* The individual is between 18 and 65 years of age
* The individual's blood EPA+DPA+DHA ≤ 5.2% at screening

Exclusion Criteria

* The individual is unable to or refuses to provide written informed consent
* The individual has taken omega-3 supplements within 3 months of screening.
* Supplements containing any of the following sources of omega-3s will exclude the individual from the study: fish oil, flax oil, krill oil, green-lipped mussel, chia, perilla, algea
* The individual's blood EPA+DPA+DHA ≥ 5.2% at screening
* The individual is female and pregnant or breastfeeding, or plans to be during the trial period
* The individual has known allergies product ingredients (fish/seafood)
* The individual has any significant medical illness or condition
* The individual has reported a history of drug dependence or substance abuse (excluding nicotine)
* The individual is taking lipid-altering medications (statins, niacin, carnitine, fibrates etc.)
* The individual is unable to abstain from caffeine, alcohol or physical activity for 24 hours before each treatment visit
* The individual will be excluded if he or she has any additional conditions that, in the Investigator's opinion, would preclude the participant from completing the study or would not be in the best interest of the subject. This would include any significant illness or unstable medical condition that could lead to difficulty complying with the protocol
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Pharmalink International Ltd.

UNKNOWN

Sponsor Role collaborator

Nutrasource Pharmaceutical and Nutraceutical Services, Inc.

NETWORK

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Maggie D Laidlaw, Ph.D

Role: PRINCIPAL_INVESTIGATOR

Nutrasource Diagnostics

Locations

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Nutrasource Diagnostics Inc

Guelph, Ontario, Canada

Site Status

Countries

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Canada

Other Identifiers

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176412

Identifier Type: OTHER

Identifier Source: secondary_id

12-02-003

Identifier Type: OTHER

Identifier Source: secondary_id

11.0202

Identifier Type: -

Identifier Source: org_study_id