Comparative Effectiveness of Neuroprotectants on Acute Ischemic Stroke

NCT ID: NCT01556854

Last Updated: 2012-03-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

20000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-07-31

Study Completion Date

2014-06-30

Brief Summary

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The primary objective of this study is to compare effectiveness of five different neuroprotectants, including butylphthalide, edaravone, citicoline, cerebrolysin, and piracetam, among patients with acute ischemic stroke.

The secondary objectives of the study are as follows:

* To compare safety of five different neuroprotectents, including butylphthalide, edaravone, citicoline, cerebrolysin, and piracetam, among patients with acute ischemic stroke.
* To compare cost-effectiveness of five different neuroprotectents, including butylphthalide, edaravone, citicoline, cerebrolysin, and piracetam, among patients with acute ischemic stroke.

Detailed Description

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Study Population:The study population will consist of consenting patients who are on neuroprotectant injection for the treatment of acute IS during hospitalization. Hospitals may contribute differing numbers of patients to the total sample size. Primary analyses will be conducted on the total sample size only.

Assessment of Outcomes:The outcome measures in this study include effectiveness, safety and cost measures.

Conditions

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Acute Ischemic Stroke

Study Design

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Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* At least 18 years old
* Ischemic stroke confirmed by brain CT or MRI within 14 days of the index event
* Neuroprotectents administrated during hospitalization
* Direct admission based on physician evaluation or arrival through the emergency department
* Ability of patient or legally authorized representative (primarily spouse, parents, adult children, otherwise indicated) to provide informed consent.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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yongjun wang

OTHER_GOV

Sponsor Role lead

Responsible Party

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yongjun wang

Beijing Tiantan hospital

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Tiantan hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Facility Contacts

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Yilong Wang, Doctor

Role: primary

00861067098222

Other Identifiers

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2011BAI08B02-01

Identifier Type: -

Identifier Source: org_study_id

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