Post Market Study of the 3DKnee™ With E-plus Insert

NCT ID: NCT01551472

Last Updated: 2022-03-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

TERMINATED

Total Enrollment

175 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-04-30

Study Completion Date

2022-01-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to evaluate the use and efficacy of the 3DKnee™ System using Vitamin E UHMWPE tibial inserts for total knee replacement surgery.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Total knee replacement surgery is widely accepted as effective treatment for degenerative joint disease (DJD), osteoarthritis and rheumatoid arthritis. Relief of patient pain and return of mobility are the primary goals that can be accomplished by this surgery. Currently available prosthetic designs accomplish these goals and the surgery has been defined as one of the most successful operations available to improve the quality of life for patients with DJD. This study will evaluate subjects who are candidates for a total knee replacement and meet the indications for use criteria for the 3DKnee™ System with vitamin E UHMWPE tibial inserts (VE).

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Degenerative Joint Disease Osteoarthritis Traumatic Arthritis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

3DKnee™ with e-plus Insert

Subjects who meet the indications for use criteria for the 3DKnee™ System with vitamin E UHMWPE tibial inserts (VE) and who are candidates for a primary knee arthroplasty.

3DKnee™ System with Vitamin E UHMWPE Tibial Inserts

Intervention Type DEVICE

This device is part of a total knee replacement system utilized in treating patients who are candidates for primary cemented total knee arthroplasty or revision arthroplasty where bone loss is minimal and the collateral ligaments are intact. It is intended to aid the surgeon in relieving the patient of knee pain and restoring knee joint function.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

3DKnee™ System with Vitamin E UHMWPE Tibial Inserts

This device is part of a total knee replacement system utilized in treating patients who are candidates for primary cemented total knee arthroplasty or revision arthroplasty where bone loss is minimal and the collateral ligaments are intact. It is intended to aid the surgeon in relieving the patient of knee pain and restoring knee joint function.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Subject must be a candidate for a total primary knee replacement.
* Subject must have knee joint disease related to degenerative joint disease, including osteoarthritis or traumatic arthritis
* Subject has a BMI ≤ 40.00 kg/m2
* Subject is likely to be available for evaluation for the duration of the study
* Subject is able and willing to sign the informed consent and follow study procedures
* Subject is not pregnant
* Subject must be between age 40 and age 75 at the time of consent

Exclusion Criteria

* Subject has had a prior total or uni-knee replacement on this knee in the past (no revisions allowed in study)
* Subject has avascular necrosis of the femoral condyles, post-traumatic loss of joint configuration, particularly when there is patellofemoral erosion, dysfunction or prior patellectomy, moderate valgus, varus, or flexion deformities or rheumatoid arthritis
* Subject has an active cancer or is a survivor for \<5 years except for squamous cell or basal cell skin cancer
* Subject has a chronic disease(s) where, in the opinion of the investigator, the disease will interfere with the patient's ability to follow the protocol
* Subject is currently a documented substance abuser (alcohol or other addictions)
* Subject has an infection, or history of infection (within the last 3 months), acute or chronic, local or systemic
* Subject has a history of muscular, neurological or vascular deficiencies which compromise the affected extremity
* Subject has a BMI \> 40.00 kg/m2
* Subject has loss of ligamentous structures
* Subject has high levels of physical activity and is unwilling to modify levels of physical activity commensurate with recommendations
* Subject has a mental condition that may interfere with the subject's ability to give an informed consent or willingness to fulfill the study requirements (i.e., severe mental retardation such that the Subject cannot understand the informed consent process, global dementia, prior strokes that interfere with the Subject's cognitive abilities, senile dementia, and Alzheimer's Disease)
* Subject is a prisoner
* Subject is pregnant
* Subject has known materials sensitivity (to metals)
* Subject is younger than 40 years (\<40) or older than 75 years (\>75) at the time of consent
Minimum Eligible Age

40 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

DJO Incorporated

INDUSTRY

Sponsor Role collaborator

Encore Medical, L.P.

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Orthopaedic Surgery Specialists

Burbank, California, United States

Site Status

Orthopedic Specialists of North County

Oceanside, California, United States

Site Status

Institute for Orthopaedic Surgery and Sports Medicine

Fort Myers, Florida, United States

Site Status

St. Peter's Bone & Joint Surgery

City of Saint Peters, Missouri, United States

Site Status

New Mexico Orthopedics

Albuquerque, New Mexico, United States

Site Status

Texas Institute for Hip and Knee Surgery

Austin, Texas, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

PS-706

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Polyethylene Wear Particle Analysis of TKA
NCT06426641 ACTIVE_NOT_RECRUITING
Journey™ UNI Post Market Clinical Follow-Up
NCT03442231 ACTIVE_NOT_RECRUITING
MDR Vivacit-E Elevated Study
NCT07150221 ENROLLING_BY_INVITATION