Physical Activity and Basal Metabolic Rate in Postmenopausal Women
NCT ID: NCT01550536
Last Updated: 2023-11-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
49 participants
INTERVENTIONAL
2008-01-31
2010-08-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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Training
Sedentary women who exercised \<2 hours per week and who had never engaged in a regular exercise program were enrolled in an exercise training intervention, following baseline measurements. See intervention below.
Resistance and aerobic exercise
Following baseline measurements, sedentary women were enrolled in a 16-week exercise training program at the YMCA in La Jolla, CA. Exercise occurred 3 times per week, for 1.5 hours each time. Exercise consisted of stretching, 20 minutes of aerobic exercise on elliptical machines, and 3 sets of 10-12 repetitions to failure for each of ten weight lifting exercises: abdominal crunch, arm curl, arm extension, chest press, lat pull-down, leg curl, leg extension, leg press, seated row, and trunk extension. Women started at 65-75% of 1-repetition-maximum, and resistance was increased as necessary to maintain the number of sets and reps and to continue to work to failure. Exercise was monitored by a TechnoGym electronic key system, and trainers instructed and supervised subjects in the gym.
Active
Postmenopausal women who exercised \>5 hours per week and had been doing so for at least the past 10 years. These women were asked to maintain their normal activity habits for the duration of the study.
No interventions assigned to this group
Interventions
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Resistance and aerobic exercise
Following baseline measurements, sedentary women were enrolled in a 16-week exercise training program at the YMCA in La Jolla, CA. Exercise occurred 3 times per week, for 1.5 hours each time. Exercise consisted of stretching, 20 minutes of aerobic exercise on elliptical machines, and 3 sets of 10-12 repetitions to failure for each of ten weight lifting exercises: abdominal crunch, arm curl, arm extension, chest press, lat pull-down, leg curl, leg extension, leg press, seated row, and trunk extension. Women started at 65-75% of 1-repetition-maximum, and resistance was increased as necessary to maintain the number of sets and reps and to continue to work to failure. Exercise was monitored by a TechnoGym electronic key system, and trainers instructed and supervised subjects in the gym.
Eligibility Criteria
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Inclusion Criteria
* FSH \> 30 mIU/ml
* estradiol-17β \< 25 pg/ml
Exclusion Criteria
* hypo- or hyperthyroid (serum TSH \< 0.3 or \> 5.5 microU/ml, respectively)
* underweight or severely obese (BMI \< 18.5 or \> 35 kg/m2, respectively)
* weight instability within the past six months (±\> 5% of body weight)
* hormone replacement therapy within the past six months
* history of metabolic, respiratory or cardiovascular disease
* high blood pressure
* contraindication for maximal aerobic testing as determined by PAR-Q questionnaire and physician's examination
40 Years
120 Years
FEMALE
Yes
Sponsors
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Wenner Gren
UNKNOWN
Sigma Xi
UNKNOWN
National Center for Research Resources (NCRR)
NIH
University of California, San Diego
OTHER
Responsible Party
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Andrew Froehle
Doctoral Candidate
Principal Investigators
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Andrew W Froehle, PhD
Role: PRINCIPAL_INVESTIGATOR
University of California, San Diego
Locations
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La Jolla YMCA
La Jolla, California, United States
UCSD Human Exercise Physiology Laboratory
La Jolla, California, United States
UCSD General Clinical Research Center
San Diego, California, United States
Countries
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References
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Froehle AW, Ngo HT, Hopkins SR, Natarajan L, Schoeninger MJ. 2010. Relationship between physical activity, body composition and basal metabolic rate in postmenopausal women. Am J Hum Biol 22:252-253. [meeting abstract]
Froehle AW, Ngo HT, Natarajan L, Schoeninger MJ, Hopkins SR. 2011. Short-term exercise does not elevate basal metabolic rate (BMR) in postmenopausal women in the absence of increased fat free mass (FFM). Am J Hum Biol 23:259. [meeting abstract]
Other Identifiers
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UCSD GCRC 1910/6766
Identifier Type: -
Identifier Source: org_study_id