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Evaluation of the Cone Outer Segment Tips Line After Epiretinal Membrane Surgery

NCT ID: NCT01549249

Last Updated: 2012-11-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

333 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-06-30

Study Completion Date

2011-11-30

Brief Summary

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The recovery of the cone outer segment tips (COST) line after epiretinal membrane (ERM) surgery using spectral-domain optical coherence tomography (SD-OCT) was assessed.

Detailed Description

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Epiretinal membrane (ERM) may cause decreased central vision or metamorphopsia. Pars plana vitrectomy with membrane peeling has become the standard treatment for epiretinal membrane. However, visual recovery or symptomatic relief is not always satisfactory in all eyes despite successful membrane removal. Spectral domain optical coherence tomography (SD-OCT) is a non-invasive imaging device for various vitreoretinal diseases. Cone outer segment tips (COST) line is a line observed between IS/OS line and RPE in SD-OCT. The investigators examined the correlation of visual acuity and the recovery of photoreceptor layer after ERM surgery, taking COST line into account as a new parameter

Conditions

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Epiretinal Membrane

Keywords

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cone outer segment tips line inner segment/outer segment junction line optical coherence tomography epiretinal membrane

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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vitrectomy

Group Type NO_INTERVENTION

optical coherence tomography

Intervention Type DEVICE

spectral-domain optical coherence tomography

Interventions

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optical coherence tomography

spectral-domain optical coherence tomography

Intervention Type DEVICE

Other Intervention Names

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vitreous surgery

Eligibility Criteria

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Inclusion Criteria

* Patients who received epiretinal membrane surgery between June, 2008, and November, 2010, at Kyorin Eye Center.
* Only eyes with postoperative follow-up period more than 6 months were included.

Exclusion Criteria

* Eyes with secondary epiretinal membrane (previous history of uveitis, intraocular surgery, pre-operatively noted retinal breaks, etc.) were excluded.
Minimum Eligible Age

40 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kyorin University

OTHER

Sponsor Role lead

Responsible Party

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Makoto Inoue

Associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Makoto Inoue, MD

Role: PRINCIPAL_INVESTIGATOR

Kyorin Eye Center

Locations

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Kyorin Eye Center

Mitaka, Tokyo, Japan

Site Status

Countries

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Japan

References

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Itoh Y, Inoue M, Rii T, Hirota K, Hirakata A. Correlation between foveal cone outer segment tips line and visual recovery after epiretinal membrane surgery. Invest Ophthalmol Vis Sci. 2013 Nov 5;54(12):7302-8. doi: 10.1167/iovs.13-12702.

Reference Type DERIVED
PMID: 24106115 (View on PubMed)

Other Identifiers

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KyorinEye007

Identifier Type: -

Identifier Source: org_study_id