Internet-CBT (Cognitive Behavioral Therapy) for Depression and Anxiety in Parkinsons Disease

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

150 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-02-29

Study Completion Date

2013-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this project is to develop and evaluate Internet-based Cognitive Behavioral Therapy (ICBT) for Parkinson's Disease (PD) patients with concurrent depression or anxiety symptoms. All treatment in this project is given as an adjunct to Standard Medical Treatment (SMT). ICBT will be compared to an Internet-based active control treatment (ICONTROL) and to SMT alone. It is hypothesized that both active treatments will be superior to SMT, and that ICBT will be superior to ICONTROL, in reducing symptoms of depression and anxiety.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Cognitive Behavioral Therapy for Depression in Parkinson's Disease

NCT00810628

Parkinson's Disease Depression

TERMINATED NA

Telehealth Psychotherapy for Depression in Parkinson's Disease

NCT03993041

Depression Parkinson's Disease

COMPLETED NA

iCBT for Depression - Standard Versus Condensed Treatment Material

NCT01788657

Major Depression

COMPLETED NA

Telehealth Cognitive Behavioral Therapy for Depression in Parkinson's Disease (PD)

NCT02475954

Depression Parkinson's Disease

COMPLETED NA

Internet-based Psychodynamic Therapy Compared to Behavioral Activation - a Randomized Controlled Trial

NCT05109741

Depression

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Parkinson's Disease Depression Anxiety Insomnia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

ICBT

Internet-based Cognitive Behavioral Therapy with a focus on behavioral activation

Group Type EXPERIMENTAL

ICBT

Intervention Type BEHAVIORAL

12 weeks of Internet-based Cognitive Behavioral Therapy with a focus on behavioral activation

ICONTROL

Internet-based treatment with a focus on relaxation training

Group Type ACTIVE_COMPARATOR

ICONTROL

Intervention Type BEHAVIORAL

12 weeks of Internet-based treatment with a focus on relaxation training

SMT

Standard Medical Treatment while being on the waitlist for randomization to any of the active treatments

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

ICBT

12 weeks of Internet-based Cognitive Behavioral Therapy with a focus on behavioral activation

Intervention Type BEHAVIORAL

ICONTROL

12 weeks of Internet-based treatment with a focus on relaxation training

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Clinical diagnosis of Parkinson's Disease
* At least mild to moderate depression or anxiety defined as HADS-A or HADS-D \> 7

Exclusion Criteria

* Has a high alcohol or drug use assessed by the AUDIT / DUDIT and assessment interview
* Somatic or psychiatric problems that are directly contraindicated or seriously hamper the implementation of the treatment (eg, psychotic disorders or bipolar disorder)
* Difficulties that hamper the use of a computer
* The patient states difficulties in finding enough time for treatment
* Too low cognitive functioning defined as MoCA \< 24
* Too severe depression, defined as MADRS-S over 30
* Too high suicidal risk defined as more than 4 points on the MADRS-S question 9 or according to the structured assessment interview

Eligible Sex

ALL

Accepts Healthy Volunteers

No