Drug Utilization of Boceprevir and Clinical Management of Health Outcomes of Interest in Chronic Hepatitis C Participants (P08518)

NCT ID: NCT01544582

Last Updated: 2016-09-16

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

713 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-05-31

Study Completion Date

2015-07-31

Brief Summary

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This is an observational prospective follow-up study to assess the utilization of boceprevir and the management of pre-specified health outcomes of interest (HOIs) under conditions of routine clinical care in participants with chronic hepatitis C (CHC) genotype 1.

As an observational prospective study, this study is not intended to change the participant/physician relationship, nor influence the physician's drug prescription or therapeutic management of the participant. No individual administration of any therapeutic or prophylactic agent is assigned in this protocol, and there are no procedures required as part of this protocol. Physician choice of the drug used to treat the participant is based on clinical judgment alone.

Detailed Description

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Conditions

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Hepatitis C Chronic

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Boceprevir + PR

CHC genotype-1 participants included in study and prescribed boceprevir plus PR as routine clinical management.

No interventions assigned to this group

Telaprevir + PR

CHC genotype-1 participants included in study and prescribed telaprevir plus PR as routine clinical management.

No interventions assigned to this group

PR Alone

CHC genotype-1 participants included in study and prescribed PR alone as routine clinical management.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Documented chronic hepatitis C (CHC) genotype-1 infection
* Untreated or failed previous therapy
* Initiated a new treatment regimen after the study implementation date at their site
* Agrees to participate in the study by giving written informed consent

Exclusion Criteria

* Taking part in a clinical trial or in any study where a participant is receiving care outside of normal clinical practice for Hepatitis C Virus (HCV)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Merck Sharp & Dohme LLC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Medical Director

Role: STUDY_DIRECTOR

Merck Sharp & Dohme LLC

Other Identifiers

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EP08043.001

Identifier Type: OTHER

Identifier Source: secondary_id

SCH 503034 P08518

Identifier Type: OTHER

Identifier Source: secondary_id

MK-3034-072

Identifier Type: OTHER

Identifier Source: secondary_id

P08518

Identifier Type: -

Identifier Source: org_study_id

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