Vitamin D Supplementation and Regulatory FoxP3+ T Cells in the GUT
NCT ID: NCT01538485
Last Updated: 2012-10-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
16 participants
INTERVENTIONAL
2012-01-31
2012-08-31
Brief Summary
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Detailed Description
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The primary goal is to evaluate the influence of vitamin D supplementation on the regulatory FoxP3+ T cells in the gastrointestinal mucosa under controlled conditions within 2 months.
The secondary study goals are to evaluate the effect of vitamin D supplementation on peripheral induced tregs and on other important immune cells in the tissue (NK, NKT cells and LPCD) and in the blood (NK, NKT cells, Th17, Th1, Th2 cells) within 2 months.
Conditions
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Keywords
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Study Design
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NA
SINGLE_GROUP
PREVENTION
NONE
Study Groups
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Cholecalciferol
Cholecalciferol
weekly dose (based on 70IU KG body weight/day)
Interventions
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Cholecalciferol
weekly dose (based on 70IU KG body weight/day)
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* non smoker
* BMI: 20-30 kg/m²
* Healthy
Exclusion Criteria
* pregnancy
* chronic diseases
18 Years
40 Years
ALL
Yes
Sponsors
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Medical University of Graz
OTHER
Responsible Party
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Principal Investigators
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Thomas R. Pieber, Prof.
Role: PRINCIPAL_INVESTIGATOR
Medical University of Graz
Locations
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Medical university Graz
Graz, , Austria
Countries
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Other Identifiers
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ADPP 003: GUT
Identifier Type: -
Identifier Source: org_study_id