Caris Biorepository Research Protocol

NCT ID: NCT01499394

Last Updated: 2026-01-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

100000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-11-30

Study Completion Date

2035-11-30

Brief Summary

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The Biorepository for Caris Life Sciences is designed for the purpose of making quality biospecimens and associated clinical data available for research studies related to advancing precision medicine and improving care for patients.

The Caris Biorepository is a repository of prospectively collected biological specimens and associated clinical and demographic data gathered from multiple sources to be stored, used and shared for research. Caris Life Sciences will maintain the data and specimens and will control access to and use of the information and specimens by multiple individuals for multiple purposes which may evolve over time.

Detailed Description

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The Caris Biorepository is an effort toward defining the future of medicine incorporating the discoveries of the genomic era by providing physicians, researchers and scientists access to quality human specimens and data aimed at improving human health and fighting disease. This will be accomplished through acquiring and sharing valuable biospecimen information and clinical outcomes in a collaborative, secure environment. The Caris Biorepository will bridge the gap and correlate human specimens with clinical and specimen data valuable to multiple and varying entities interested in advancing science with precision medicine by targeting disease treatments.

The objective of this project is to develop and implement a state-of-the-science Biorepository that ensures molecular integrity and clinical relevance of human biospecimens used in research and clinical medicine. The Caris Biorepository will also provide vital biospecimens and data to internal researchers and external research collaborators such as government, academia and industry collaborators for the use of drug development discoveries, clinically relevant research trials, publications and posters, and the implementation of future healthcare policies. This project may also impact characterization of trends in practice patterns and their relation to patient outcomes as well as the economic implications of differing evaluation, treatment and management paradigms.

Conditions

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Cancer Early Detection of Cancer Minimal Residual Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Normal

Donor samples reflective of a "normal" non-disease state

No interventions assigned to this group

Newly Diagnosed Pan-Cancer Collection

Donor samples derived from treatment naïve patients with newly diagnosed solid tumors.

No interventions assigned to this group

Early Detection Collection

Donor samples reflective of a population at increased risk for developing cancer.

No interventions assigned to this group

Advanced Stage Cancer Collection

Donor samples derived from individuals with advanced stage cancer.

No interventions assigned to this group

Minimal Residual Disease Collection

Donor samples obtained from individuals with a history of malignancy who are currently free of active disease

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* 18 years of age or older
* Capacity to provide informed consent

Exclusion Criteria

* Due to the complexity of state and federal requirements governing the participation of prisoners in research, prisoners-patients will not be approached for participation in the Caris Biorepository.
* Minor subjects will not be included in the Caris Biorepository, as it is possible biospecimens and data may be stored beyond the time limitations of assent and it may be impracticable to re-consent these subjects once they become adults.
* Individuals who lack the capacity to give informed consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Caris Science, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Matthew Oberley, MD

Role: PRINCIPAL_INVESTIGATOR

Caris Life Sciences

Locations

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University of South Alabama

Mobile, Alabama, United States

Site Status RECRUITING

Southwest Medical Imaging

Scottsdale, Arizona, United States

Site Status RECRUITING

St. Bernards Medical Center

Jonesboro, Arkansas, United States

Site Status RECRUITING

CARTI Cancer Center

Little Rock, Arkansas, United States

Site Status RECRUITING

ObjectiveHealth - ARcare Center for Clinical Research

Little Rock, Arkansas, United States

Site Status RECRUITING

Lee Memorial Health System

Fort Myers, Florida, United States

Site Status RECRUITING

Cancer Care of North Florida

Lake City, Florida, United States

Site Status RECRUITING

Advent Health

Orlando, Florida, United States

Site Status RECRUITING

The University of South Florida

Tampa, Florida, United States

Site Status RECRUITING

Cleveland Clinic Florida

Weston, Florida, United States

Site Status RECRUITING

Phoebe Putney Memorial Hospital

Albany, Georgia, United States

Site Status RECRUITING

Emory University

Atlanta, Georgia, United States

Site Status RECRUITING

Augusta University Research Institute

Augusta, Georgia, United States

Site Status RECRUITING

Cancer Center of Middle Georgia

Dublin, Georgia, United States

Site Status RECRUITING

Hope and Healing Cancer Services

Hinsdale, Illinois, United States

Site Status RECRUITING

CHRISTUS - St. Frances Cabrini Hospital

Alexandria, Louisiana, United States

Site Status RECRUITING

Tulane University

New Orleans, Louisiana, United States

Site Status RECRUITING

CHRISTUS - Highland Medical Center

Shreveport, Louisiana, United States

Site Status RECRUITING

Mercy Medical Center

Baltimore, Maryland, United States

Site Status RECRUITING

Sinai Hospital of Baltimore

Baltimore, Maryland, United States

Site Status RECRUITING

Hattiesburg Clinic

Hattiesburg, Mississippi, United States

Site Status RECRUITING

Jackson Oncology Associates

Jackson, Mississippi, United States

Site Status RECRUITING

University of Mississippi Medical Center

Jackson, Mississippi, United States

Site Status RECRUITING

ObjectiveHealth - Premier Health Research

Sparta, New Jersey, United States

Site Status RECRUITING

CHRISTUS - St. Vincent Regional Cancer Center

Santa Fe, New Mexico, United States

Site Status RECRUITING

St. Lawrence Health System

Potsdam, New York, United States

Site Status RECRUITING

National Translational Research Group

Ridge, New York, United States

Site Status RECRUITING

Altru Health System

Grand Forks, North Dakota, United States

Site Status RECRUITING

NEO Urology Associates

Boardman, Ohio, United States

Site Status RECRUITING

Great Lakes Medical Research

Cleveland, Ohio, United States

Site Status RECRUITING

Bend Memorial Clinic

Bend, Oregon, United States

Site Status RECRUITING

Clinical Biotechnology Research Institute at RSFH

Charleston, South Carolina, United States

Site Status RECRUITING

Spartanburg Regional Health Services

Spartanburg, South Carolina, United States

Site Status RECRUITING

West Cancer Center

Germantown, Tennessee, United States

Site Status RECRUITING

ObjectiveHealth - Amarillo Premier Research

Amarillo, Texas, United States

Site Status RECRUITING

CHRISTUS - St. Michael's Health

Texarkana, Texas, United States

Site Status RECRUITING

CAMC Clinical Trials

Charleston, West Virginia, United States

Site Status RECRUITING

Mercy Health

Janesville, Wisconsin, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Mary Baker

Role: CONTACT

Facility Contacts

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Tiffany Fulford

Role: primary

251-445-3276

Emily Crampton

Role: primary

480-425-4055

Dashae King

Role: primary

870-207-8157

Jesse Byrd

Role: primary

501-561-2205

Cynthia Whitcomb

Role: primary

501-214-0372

Juliana Turner

Role: primary

239-343-9660

Natalie Espenship

Role: primary

386-755-1655

Corina Mattix

Role: primary

407-303-1327

Brittney Short

Role: primary

727-612-4026

Brianna Hammond

Role: primary

954-487-2257

Cathy Shoemaker, OCN CBCN

Role: primary

229-312-0354

Sharon Egbue-Ojirogbe

Role: primary

404-778-8027

Alexander Ward

Role: primary

706-721-1623

Audrey Bryan

Role: primary

478-272-8266 ext. 321

Ava Baftirovska

Role: primary

630 560 0121 ext. 107

Crystal Dubois

Role: primary

318-528-5137

Priya Bhandari

Role: primary

504-988-6053

Thea Spencer

Role: primary

318-681-6007

Rhiannon Kim

Role: primary

410-951-7908

Pamela Nickoles

Role: primary

410-601-6120

Gloria Simmons

Role: primary

601-288-2494

Teresa Davis

Role: primary

601-974-5547

Tanya Robinson

Role: primary

601-815-2123

Lori Walsh

Role: primary

862-294-0418

MiQuela Gutierrez

Role: primary

505-913-8822

McKenna Boula

Role: primary

315-261-6319

Stella Smaragdas

Role: primary

631-675-5103

Alexis Tatum

Role: primary

701-780-1563

Tina Picino

Role: primary

330-729-9214 ext. 240

Cortney Vazquez

Role: primary

216-372-0505

Madison Cox

Role: primary

541-706-5339

Aindrea Maddray

Role: primary

843-724-2204

Kamara Mertz-Rivera

Role: primary

864-560-6104

Melissa Smith

Role: primary

901-683-0055 ext. 62739

Lauren Kuehler

Role: primary

806-641-0256

Kimberly Everett

Role: primary

903-614-6885

Kristi Sutphin

Role: primary

304-388-9945

Ashli Huppert

Role: primary

608-756-6695

Other Identifiers

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TCBIO-001-0710

Identifier Type: -

Identifier Source: org_study_id

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