The Effect of Marketing Variable on Effect of Active Drugs

NCT ID: NCT01493908

Last Updated: 2011-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

220 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-01-31

Study Completion Date

2013-06-30

Brief Summary

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The efficacy of the placebo effect has been proved in many prior studies by comparing the symptoms and measures of patients. Placebo has been proved to help in treating illnesses such as depression, stomach ulcer and chronic headaches.

A Meta analysis checked 47 studies about placebo and showed great significance when a patient is treated with placebo pill, no active substance, just by activating conditioning and expectation mechanism in his body, thus providing to the healing process, and that is it's importance.

In recent years studies established a relationship between marketing variables (such as price, label) to the efficacy of a product. In addition- a unique research run in 2008 showed a significant relationship between the marketing strategies and the efficacy of medication; more specifically, patients in this research experienced less (controlled) pain when treated with placebo medication introduced to them as more expensive than patients treated with placebo medication that was introduced to them as much cheaper. All patients were treated with the exact same medication.

In the investigator's experiment the investigators design a laboratory experiment to determine if marketing factors could invoke the placebo effects described earlier. For the initial laboratory experiment, we decided to examine the difference in price, on the efficacy of an OTC analgesic through the mediation of low- voltage electrical pulses to the patient's wrist.

The investigators study hypothesis is that marketing variables such as price and brand name will affect the therapeutic efficacy of an analgesic, i.e. a medicine will have greater influence when the patient is aware of its price compared to one who is not.

Detailed Description

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Conditions

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Pain

Keywords

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Placebo effect; Pain; Analgesic; Electrical shock control in healthy volunteers

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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High price

Group Type ACTIVE_COMPARATOR

High price

Intervention Type DRUG

Acetaminophen label as high price

Low price

Group Type ACTIVE_COMPARATOR

Low price

Intervention Type DRUG

Acetaminophen label as low price

Low price participants aware paying part

Group Type ACTIVE_COMPARATOR

Low price participants aware paying part

Intervention Type DRUG

Acetaminophen label as low price; participants aware they are paying part of the full price

No price

Group Type ACTIVE_COMPARATOR

No price

Intervention Type DRUG

acetaminophen. No price - price issue not introduced to participants.

Free of charge

Group Type ACTIVE_COMPARATOR

Free of charge

Intervention Type DRUG

Acetaminophen. participants aware the product is free of charge

Interventions

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High price

Acetaminophen label as high price

Intervention Type DRUG

Low price

Acetaminophen label as low price

Intervention Type DRUG

Low price participants aware paying part

Acetaminophen label as low price; participants aware they are paying part of the full price

Intervention Type DRUG

No price

acetaminophen. No price - price issue not introduced to participants.

Intervention Type DRUG

Free of charge

Acetaminophen. participants aware the product is free of charge

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Healthy Volunteer participants will be between the ages of 18 and 65

Exclusion Criteria

* Candidates who have had a history of cardiac problems, epilepsy, diabetes, or are pregnant will be excluded.
* Taking no pain medication at the time of the experiment.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hadassah Medical Organization

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Amnon - Lahad, MD, MPH

Role: PRINCIPAL_INVESTIGATOR

Hebrew University, Jerusalem Israel

Locations

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Department of Family Medicine, Hebrew University, JerusaelmIsrael

Jerusalem, , Israel

Site Status

Countries

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Israel

Central Contacts

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Amnon - Lahad, MD, MPH

Role: CONTACT

Phone: +972-2-6758505

Email: [email protected]

Hadas - Lemberg, PhD

Role: CONTACT

Phone: 00 972 2 6777572

Email: [email protected]

Facility Contacts

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Amnon - Lahad, MD, MPH

Role: primary

Hadas Lemberg, PhD

Role: backup

Other Identifiers

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1727-HMO-CTIL

Identifier Type: -

Identifier Source: org_study_id