Differences in Nerve Fiber Layer Between Patients With Normal- and High-Pressure-Glaucoma

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

44 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-03-31

Study Completion Date

2011-11-30

Brief Summary

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The purpose of the study is to prove if there is any difference in the nerve fiber layer between patients with normal- and high-tension-glaucoma with similar structural optic nerve head parameters.

Detailed Description

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It is till now not definitely clear whether normal- and high-tension glaucoma are different forms of the same disease and whether they have similar pathogenetic mechanisms. Spectral domain optical coherence tomography (SD-OCT) is supposed to objectively evaluate retinal nerve fiber layer (RNFL) thickness. The investigators propose a study to compare the RNFL in patients with normal- and high-tension-glaucoma. In order to exclude other possible differences,which could influence the results, only patients with similar structural optic nerve head damage in both groups will be compared.

Conditions

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Normal Tension Glaucoma High Tension Glaucoma

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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high-tension glaucoma

subjects with IOP\>22 mmHg without eyedrops and signs of glaucomatous optic nerve damage

No interventions assigned to this group

low-tension glaucoma

subjects with IOP\<22 mmHg without eyedrops and signs of glaucomatous optic nerve damage

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* persons over 18 years
* men or women
* with normal- and high-tension glaucoma

Exclusion Criteria

* cataract
* cloudy cornea and other conditions with bad visualisation quality of optic nerve head
* optic nerve atrophy except glaucomatous

Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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EK 322102010

Identifier Type: -

Identifier Source: org_study_id