Evaluation of the Performance of Two Contact Lenses Compared to a Marketed Lens

NCT ID: NCT01484028

Last Updated: 2018-06-19

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

275 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-11-30

Study Completion Date

2012-02-29

Brief Summary

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This study will serve to evaluate and compare the performance of two new lenses to a marketed lens.

Detailed Description

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Conditions

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Refractive Ametropia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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EALE/1DM

etafilcon A with PVP for light eyes worn during the first period of 7-9 days then etafilcon A control lens worn during the second period of 7-9 days, with a 1-3 days of wash-out time between the 2 periods.

Group Type OTHER

etafilcon A control lens (1DM)

Intervention Type DEVICE

A marketed daily disposable contact lens

etafilcon A with print and PVP for light eyes (EALE)

Intervention Type DEVICE

A daily disposable contact lens

1DM/EALE

etafilcon A control lens worn during the first period of 7-9 days then etafilcon A with PVP for light eyes worn during the second period of 7-9 days, with a 1-3 days of wash-out time between the 2 periods.

Group Type OTHER

etafilcon A control lens (1DM)

Intervention Type DEVICE

A marketed daily disposable contact lens

etafilcon A with print and PVP for light eyes (EALE)

Intervention Type DEVICE

A daily disposable contact lens

EADE/1DM

etafilcon A with PVP for dark eyes worn during the first period of 7-9 days then etafilcon A control lens worn during the second period of 7-9 days, with a 1-3 days of wash-out time between the 2 periods.

Group Type OTHER

etafilcon A control lens (1DM)

Intervention Type DEVICE

A marketed daily disposable contact lens

etafilcon A with print and PVP for dark eyes (EADE)

Intervention Type DEVICE

A daily disposable contact lens

1DM/EADE

etafilcon A control lens worn during the first period of 7-9 days then etafilcon A with PVP for dark eyes worn during the second period of 7-9 days, with a 1-3 days of wash-out time between the 2 periods.

Group Type OTHER

etafilcon A control lens (1DM)

Intervention Type DEVICE

A marketed daily disposable contact lens

etafilcon A with print and PVP for dark eyes (EADE)

Intervention Type DEVICE

A daily disposable contact lens

Interventions

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etafilcon A control lens (1DM)

A marketed daily disposable contact lens

Intervention Type DEVICE

etafilcon A with print and PVP for light eyes (EALE)

A daily disposable contact lens

Intervention Type DEVICE

etafilcon A with print and PVP for dark eyes (EADE)

A daily disposable contact lens

Intervention Type DEVICE

Other Intervention Names

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1-DAY ACUVUE MOIST Brand Contact Lenses

Eligibility Criteria

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Inclusion Criteria

* Healthy, female adult, at least 18 years of age, and no more than 34 years of age
* The subjects must be female, light eye Caucasian, Non-Hispanic, habitual soft contact lens wearer (both eyes) with light or dark eyes
* Must have rated the Concept Statement positively (i.e., a rating of 4 or 5).
* Optimal vertexed spherical equivalent distance correction must be between -1.00 and -4.00 diopters (D)
* Any cylinder power must be: \<=0.75D
* Visual acuity must be best correctable to 20/25 or better for each eye
* Must have normal eyes (no ocular medications or ocular infection of any type)
* Must read and sign the Statement of Informed Consent
* Must appear able and willing to adhere to the instructions set forth in this clinical protocol.

Exclusion Criteria

* Ocular or systemic allergies or disease which might interfere with contact lens wear
* Systemic disease, autoimmune disease, or use of medication which might interfere with contact lens wear
* Clinically significant (grade 3 or worse) corneal edema, corneal neovascularization, corneal staining, or any other abnormalities of the cornea which would contraindicate contact lens wear
* Clinically significant (grade 3 or 4) tarsal abnormalities or bulbar injection which might interfere with contact lens wear
* Any ocular infection
* Any corneal distortion resulting from previous hard or rigid gas permeable contact lens wear
* Any color deficiencies (colorblindness) - to the best of the subject's knowledge
* Pregnancy or lactation
* Diabetes
* Infectious diseases (e.g. hepatitis, tuberculosis) or an immuno-suppressive disease (e.g. HIV)
* Habitual contact lens type is toric, multifocal, or is worn as extended wear.
* Subject presents with one dark iris color and one light iris color.
* Subject has heterochromia iridis (a difference in color between parts of one iris).
* The subject must not be an employee or family member of the clinical study site.
Minimum Eligible Age

18 Years

Maximum Eligible Age

34 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Johnson & Johnson Vision Care, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Advanced Optometry

Mission Viejo, California, United States

Site Status

James R Dugue, Optometrist

Mission Viejo, California, United States

Site Status

Advance Eye Care

Pismo Beach, California, United States

Site Status

Golden Vision

Sarasota, Florida, United States

Site Status

Eye Associates of Winter Park

Winter Park, Florida, United States

Site Status

Eye Care Associates

Bloomington, Illinois, United States

Site Status

Kannarr Eye Care

Pittsburg, Kansas, United States

Site Status

Vision Care

East Lansing, Michigan, United States

Site Status

Spectrum Eye Care

Jamestown, New York, United States

Site Status

Sacco Eye Group

Vestal, New York, United States

Site Status

The Eye Care Group

Grants Pass, Oregon, United States

Site Status

Dr. David W Ferris and Associates

Warwick, Rhode Island, United States

Site Status

Wishnow Sugar Group

Katy, Texas, United States

Site Status

Isthmus Eye Care

Middleton, Wisconsin, United States

Site Status

Snowy Range Cision Center

Laramie, Wyoming, United States

Site Status

Countries

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United States

Other Identifiers

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CR-005094

Identifier Type: -

Identifier Source: org_study_id

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