Trial Outcomes & Findings for Increasing Use of the Vaccine Against Herpes Zoster/Shingles at NYULMC and Bellevue Hospital (NCT NCT01483378)

NCT ID: NCT01483378

Last Updated: 2013-08-09

Results Overview

All enrolled patients completed a survey of baseline characteristics, eligibility for the herpes zoster vaccine, and attitudes regarding herpes zoster vaccination. The survey results from patients who agreed to receive the herpes zoster vaccine were compared to the results of patients who declined to be vaccinated.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

170 participants

Primary outcome timeframe

January 9, 2012 to February 12, 2012

Results posted on

2013-08-09

Participant Flow

We prospectively recruited eligible patients from the Bellevue Eye clinic until 100 patients were prescribed and received the vaccine. Recruitment occurred from January 9, 2012 to February 12, 2012.

Participant milestones

Participant milestones
Measure
Patients Who Received the Herpes Zoster Vaccine
These eligible subjects completed the survey and then chose to receive the herpes zoster vaccine for free.
Patients Who Declined the Herpes Zoster Vaccine
These eligible subjects completed the survey and then declined to receive the herpes zoster vaccine for free.
Overall Study
STARTED
100
66
Overall Study
COMPLETED
100
66
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Increasing Use of the Vaccine Against Herpes Zoster/Shingles at NYULMC and Bellevue Hospital

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Survey Participants
n=166 Participants
Age Continuous
Age
68 years
STANDARD_DEVIATION 15 • n=5 Participants
Sex: Female, Male
Female
94 Participants
n=5 Participants
Sex: Female, Male
Male
72 Participants
n=5 Participants
Region of Enrollment
United States
166 participants
n=5 Participants

PRIMARY outcome

Timeframe: January 9, 2012 to February 12, 2012

All enrolled patients completed a survey of baseline characteristics, eligibility for the herpes zoster vaccine, and attitudes regarding herpes zoster vaccination. The survey results from patients who agreed to receive the herpes zoster vaccine were compared to the results of patients who declined to be vaccinated.

Outcome measures

Outcome measures
Measure
Patients Who Received the Herpes Zoster Vaccine
n=100 Participants
Patients who chose to receive the herpes zoster vaccine completed the survey. Primary outcomes reported are statistically significant answers to the survey questions.
Patients Who Declined the Herpes Zoster Vaccine
n=66 Participants
Patients who declined to receive the herpes zoster vaccine completed the survey. Primary outcomes reported are statistically significant answers to the survey questions.
Answers to Survey Questions
Subject reported receiving flu Vaccine last year
89 Percentage of responders
Interval 83.0 to 95.0
71.2 Percentage of responders
Interval 60.0 to 82.0
Answers to Survey Questions
Reported would receive the vaccine if recommended
98 Percentage of responders
Interval 95.0 to 100.0
74 Percentage of responders
Interval 64.0 to 85.0

Adverse Events

Subjects Who Received the Herpes Zoster Vaccine

Serious events: 0 serious events
Other events: 11 other events
Deaths: 0 deaths

Subjects Who Declined the Herpes Zoster Vaccine

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure
Subjects Who Received the Herpes Zoster Vaccine
n=100 participants at risk
Subjects Who Declined the Herpes Zoster Vaccine
Skin and subcutaneous tissue disorders
Injection Site Reaction
11.0%
11/100 • Number of events 11 • 3 months
Adverse events were only collected and assessed for participants who received vaccine since there are no risks from the vaccine if the patient did not receive it.
0/0 • 3 months
Adverse events were only collected and assessed for participants who received vaccine since there are no risks from the vaccine if the patient did not receive it.

Additional Information

Dr. Elisabeth J. Cohen

NYU Langone Medical Center

Phone: 212-263-3262

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place

Restriction type: LTE60