PEEP Recruitment-comparison Between Ultrasonographic Assessment and LIP Assessment

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

17 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-10-31

Study Completion Date

2011-11-30

Brief Summary

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The purpose of this study is to compare lung recruitment in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) based on lower inflection point with transthoracic ultrasonographic assessment of lung recruitment.

Detailed Description

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Sedated and sometimes temporary relaxed patients with ALI/ARDS on mechanical ventilation in semirecumbent position are included. Lower inflection point on pressure volume loop on ventilator Draeger Evita 4 with low continuous flow on volume controlled ventilation is measured with zero PEEP. Transthoracic lung ultrasound with linear probe is proceed on both hemithoraces when mechanical ventilation based on measured PEEP is started. We compare if real lung recruitment seen by ultrasound is the same as predicted by lower inflection point.

The procedure is a part of routine everyday respiratory monitoring in our unit.

Conditions

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Acute Respiratory Distress Syndrome

Keywords

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lung ultrasonography pressure-volume loops ARDS

Study Design

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Observational Model Type

CASE_CONTROL

Eligibility Criteria

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Inclusion Criteria

* patients with diffuse ALI/ARDS on mechanical ventilation with visible lower inflection point on dynamic P-V loops

Exclusion Criteria

* preexisting parenchymal or pleural lung disease

Minimum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Bojan Rode

dr.med.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Bojan Rode, M.D.

Role: PRINCIPAL_INVESTIGATOR

Locations

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Central intensive care unit, University hospital "Sisters of Mercy"

Grad Zagreb, , Croatia

Site Status

Countries

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Croatia

References

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Bouhemad B, Brisson H, Le-Guen M, Arbelot C, Lu Q, Rouby JJ. Bedside ultrasound assessment of positive end-expiratory pressure-induced lung recruitment. Am J Respir Crit Care Med. 2011 Feb 1;183(3):341-7. doi: 10.1164/rccm.201003-0369OC. Epub 2010 Sep 17.

Reference Type RESULT

PMID: 20851923 (View on PubMed)

Other Identifiers

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Vinogradska29

Identifier Type: -

Identifier Source: org_study_id