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Daily Activities Are Sufficient to Induce Dynamic Pulmonary Hyperinflation and Dyspnea in Chronic Obstructive Pulmonary Disease Patients

NCT ID: NCT01475812

Last Updated: 2011-11-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

19 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-03-31

Brief Summary

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Introduction: Chronic obstructive pulmonary disease is a condition characterized by airflow limitation usually progressive and associated with inflammatory response of lung noxious particles. During a physical activity chronic obstructive pulmonary disease patients may develop dynamic pulmonary hyperinflation, increased dyspnea perception and decreased activity performance. The investigators hypothesize that some specific activities of daily living induce dynamic pulmonary hyperinflation in COPD patients. Objective: To measure dynamic lung hyperinflation and its influence in dyspnea perception in moderate and severe chronic obstructive pulmonary disease patients after activities of daily living. Methods: The investigators measured inspiratory capacity, dyspnea sensation, peripheral oxygen saturation, heart rate and respiratory rate in 19 chronic obstructive pulmonary disease (COPD) patients. These measurements were taken at rest and after daily living activities (such as going up and down a set of stairs, going up and down a ramp and sweeping and mopping a room).

Detailed Description

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Conditions

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Dynamic Lung Hyperinflation COPD Patients Activities of Daily Livin.

Keywords

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COPD activities of daily living pulmonary hyperinflation exercise

Study Design

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Study Time Perspective

CROSS_SECTIONAL

Study Groups

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COPD hyperinflation

Hyperinflation and ADL

Intervention Type OTHER

Assessment of dynamic pulmonary hyperinflation during activities of daily living in COPD patients.

Interventions

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Hyperinflation and ADL

Assessment of dynamic pulmonary hyperinflation during activities of daily living in COPD patients.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* COPD patients diagnosed with moderate to very severe airway obstruction according to GOLD classification (9)
* clinical stability with no clinical exacerbation during the previous 30 days prior to the beginning of the study and to sign an informed consent form

Exclusion Criteria

* Inability to perform the slow vital capacity maneuver
* excessive perceived dyspnea during the test
* arterial oxyhemoglobin saturation (SpO2) lower than 80% during activities and/or need of oxygen supplementation
Minimum Eligible Age

50 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Federal University of São Paulo

OTHER

Sponsor Role lead

Responsible Party

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Antonio A.M. Castro

Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Federal University of São Paulo

São Paulo, São Paulo/SP, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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0353/03

Identifier Type: -

Identifier Source: org_study_id