Pulmonary Pathophysiology and Inflammatory Response in Patients Treated With Ecmo for Severe Respiratory Failure

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

6 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-02-29

Study Completion Date

2016-12-31

Brief Summary

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The purpose of this study is the observation of the course of

* the mechanics of the respiratory system
* the endexpiratory lung volume
* and the inflammatory response in patients undergoing treatment with extracorporeal life support (ECLS) due to severe refractory respiratory failure at our department.

Detailed Description

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Conditions

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Respiratory Distress Syndrome, Adult Respiratory Distress Syndrome, Child

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* patients accepted for extracorporeal life support at our department due to the most severe forms of ARDS/respiratory failure not responding to conventional therapy.

Exclusion Criteria

* malignant disease with a poor prognosis
* massive intracranial bleeding

Minimum Eligible Age

3 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Bernhard Holzgraefe

Consultant, ECMO centre Karolinska, Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Bernhard Holzgraefe, MD

Role: PRINCIPAL_INVESTIGATOR

Karolinska University Hospital

Anders Larsson, PhD

Role: STUDY_CHAIR

Uppsala University, Uppsala, Sweden

Locations

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ECMO Centre Karolinska

Solna, Stockholm County, Sweden

Site Status

Countries

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Sweden

Other Identifiers

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2011/1282-31/1

Identifier Type: -

Identifier Source: org_study_id