A Multicenter,2-Arm,Randomized,Controlled Study Evaluate the Effectiveness of the UltraShape® Contour I VER 3.1 System for Non-Invasive Reduction in Abdominal Circumference

NCT ID: NCT01462201

Last Updated: 2013-11-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

156 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-07-31

Study Completion Date

2013-10-31

Brief Summary

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The primary objective of this study is to evaluate the effectiveness of the Contour I VER 3.1 System on abdominal midsection circumference reduction relative to no treatment.

The secondary objective of this study is to assess subject satisfaction measured with a self-assessment questionnaire

Detailed Description

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Conditions

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Body Sculpting

Keywords

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focused ultrasound mechanical fat destruction Body Sculpting

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Group 1 - Non Invasive Ultrasound

Group 1 3 visits - Measurement of abdominal circumferences 3 visits - Treatment with Ultrashape Contour I VER 3.1 4 visits - Follow up visits The intervention is non invasive ultrasound.

Group Type EXPERIMENTAL

Non Invasive Ultrasound

Intervention Type DEVICE

Each treatment session is estimated to take approximately 60 minutes and will be performed on a bi-weekly basis.

Group 2 - Non Invasive Ultrasound

Group 2 3 visits - Treatment with Contour I VER 3.1 system 3 visits - Measurements of abdominal circumference 4 visits - Follow Up visits The intervention is non invasive ultrasound.

Group Type EXPERIMENTAL

Non Invasive Ultrasound

Intervention Type DEVICE

Each treatment session is estimated to take approximately 60 minutes and will be performed on a bi-weekly basis.

Interventions

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Non Invasive Ultrasound

Each treatment session is estimated to take approximately 60 minutes and will be performed on a bi-weekly basis.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Female or male subjects, 18 and 65 years of age at the time of enrollment
2. Abdominal fat thickness of at least 1.5 cm (measurement by caliper)
3. For women of child-bearing potential:

1. negative urine pregnancy test.
2. Women of child bearing age are required to be using an acceptable form of birth control for the duration of the study.
4. General good health confirmed by medical history and skin examination of the treated area
5. Written informed consent to participate in the study
6. Ability to comply with the requirements of the study
7. BMI ≤ 30


8. For women of child-bearing potential: negative pregnancy test
9. Abdominal fat thickness of at least 1.5 cm prior to initial treatment (measurement by caliper)

Exclusion Criteria

1. History of hypertension, ischemic heart disease, valvular heart disease, congestive heart failure, pacemaker/defibrillator, abdominal aortic aneurysm
2. Current hyperlipidemia, diabetes mellitus, hepatitis, liver disease, HIV positive status, blood coagulopathy or excessive bleeding, autoimmune or connective tissue disease or malignancy.
3. Previous liposuction in the treatment area
4. History of skin disease in the treatment area, known tendency to form keloids or poor wound healing
5. Skin lesions in the treatment area other than simple nevi on physical examination (e.g., atypical nevus, tattoo, abrasions) including depressed scars in the treatment area
6. Poor skin quality (i.e., laxity)
7. Abdominal wall diastasis or hernia on physical examination
8. Abnormal kidney, liver or coagulation functions, abnormal lipid profile or blood count within the last 3 months
9. Obesity (BMI \> 30)
10. Childbirth within the last 12 months or breastfeeding women.
11. Any acute or chronic condition which, in the opinion of the Investigator, could interfere with the conduct of the study
12. Unstable weight within the last 6 months (i.e., ± 3% weight change in the prior six months)
13. Inability to comply with circumference measurement procedure (e.g., inability to held breath for the required duration)
14. Participation in another clinical study within the last six months.
15. Previous body contouring treatments in the areas of the abdomen and flanks.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Syneron Medical

INDUSTRY

Sponsor Role collaborator

UltraShape

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Dr. William Patrick Coleman, III

Metairie, Louisiana, United States

Site Status

MD Laser Skin & Vein Institute

Hunt Valley, Maryland, United States

Site Status

New-Jersey Plastic Surgery

Montclair, New Jersey, United States

Site Status

Dr. Jeffrey Kenkel

Dallas, Texas, United States

Site Status

Department of Plastic Surgery and Burns Rabin Medical Center - Beilinson Hospital

Petah Tikva, , Israel

Site Status

Countries

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United States Israel

Other Identifiers

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US-0711

Identifier Type: -

Identifier Source: org_study_id