Resect and Discard Strategy in Clinical Practice

NCT ID: NCT01462123

Last Updated: 2011-10-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

286 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-02-28

Brief Summary

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Nowadays, post-polypectomy surveillance intervals are determined by combining endoscopic and pathologic data. Real-time imaging technologies, have shown promising results in discriminating adenomatous from non-adenomatous polyps.

The "resect and discard strategy" for small polyps (based on real-time assessment of the histology and on the endoscopic resection without pathological examination) has been shown to be cost-effective in simulation models. No data exist about the impact of this strategy in clinical practice.

The aim of present study was to assess whether the systematic use, in the everyday clinical practice, of the "resect and discard strategy" allows to correctly manage patients with small colonic polyps.

Detailed Description

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Conditions

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Endoscopic Assessment Colonic Polyps Endoscopic Surveillance NBI

Study Design

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Study Time Perspective

PROSPECTIVE

Study Groups

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small polyps patients

Patients with one small polyps at colonoscopy

endoscopic assessment of colonic polyps

Intervention Type OTHER

Interventions

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endoscopic assessment of colonic polyps

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* consecutive adult outpatients undergoing colonoscopy for routine clinical indications

Exclusion Criteria

* surveillance interval was not necessarily directed by endoscopic findings (history of colorectal cancer, inflammatory bowel disease, hereditary polyposis syndromes, hereditary non-polyposis colorectal cancer)
* colonoscopy was performed without NBI technology
* at least one lesion \> 10 mm or \< 10 mm but with morphologic features suspect for malignancy (depressed or ulcerated lesions) was detected
* bowel preparation was inadequate
* caecal intubation was not accomplished
* polyps could not be resected for concomitant anticoagulation treatment, 7) polyps were resected but not retrieved for pathology.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Valduce Hospital

OTHER

Sponsor Role lead

Locations

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Valduce Hospital - Gastroenterology Department

Como, CO, Italy

Site Status

Countries

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Italy

References

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Paggi S, Rondonotti E, Amato A, Terruzzi V, Imperiali G, Mandelli G, Terreni N, Lenoci N, Spinzi G, Radaelli F. Resect and discard strategy in clinical practice: a prospective cohort study. Endoscopy. 2012 Oct;44(10):899-904. doi: 10.1055/s-0032-1309891. Epub 2012 Aug 2.

Reference Type DERIVED
PMID: 22859259 (View on PubMed)

Other Identifiers

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RD 2010

Identifier Type: -

Identifier Source: org_study_id