Multicenter Study of Long-Term Clinical Outcomes of Subcutaneous Immune Globulin IgPro20 in Subjects With Primary Immunodeficiency (Japan Study)

NCT ID: NCT01461018

Last Updated: 2014-12-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

22 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-10-31

Study Completion Date

2014-07-31

Brief Summary

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The purpose of this study is to assess the long-term efficacy, tolerability, and safety of IgPro20 in subjects with primary immunodeficiency (PID) as an extension to the preceding follow-up study ZLB07\_001CR (NCT01458171).

Detailed Description

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Conditions

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Primary Immune Deficiency

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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IgPro20

Group Type EXPERIMENTAL

Immune globulin subcutaneous (Human)

Intervention Type BIOLOGICAL

IgPro20 is a 20% (weight per volume \[w/v\]) liquid formulation of human immunoglobulin for subcutaneous (SC) use.

Interventions

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Immune globulin subcutaneous (Human)

IgPro20 is a 20% (weight per volume \[w/v\]) liquid formulation of human immunoglobulin for subcutaneous (SC) use.

Intervention Type BIOLOGICAL

Other Intervention Names

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Hizentra

Eligibility Criteria

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Inclusion Criteria

* Subjects who have completed the preceding follow-up study ZLB07\_001CR.
* Written informed consent by the subject/parent/legally acceptable representative. Written assent for an underage subject (≥7 years and \<20 years of age at the time of obtaining informed consent), according to the competencies of the subject.

Exclusion Criteria

* Pregnancy or nursing mother.
* Participation in a study with an investigational medicinal product (IMP) within 3 months prior to enrollment except for study ZLB07\_001CR.
* Subjects who are planning to donate blood during the study.
* Known or suspected antibodies to the IMP, or to excipients of the IMP.
* Treatment with another immunoglobulin G (IgG) within 3 months prior to the study.
Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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CSL Behring

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Yusuke Watanabe

Role: STUDY_DIRECTOR

CSL Behring K.K.

Locations

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Study site

Nagoya, Aichi Pref., Japan

Site Status

Study site

Chiba, Chiba Pref., Japan

Site Status

Study site

Fukuoka, Fukuoka, Japan

Site Status

Study site

Gifu, Gifu Pref., Japan

Site Status

Study Site

Sapporo, Hokkaido, Japan

Site Status

Study site

Moriguchi, Osaka, Japan

Site Status

Study site

Koshigaya, Saitama Pref., Japan

Site Status

Study site

Tokorozawa, Saitama Pref., Japan

Site Status

Study site

Bunkyō City, Tokyo Metropolitan, Japan

Site Status

Countries

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Japan

Other Identifiers

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IgPro20_3006

Identifier Type: -

Identifier Source: org_study_id