Valproic Acid, Magnesium Sulphate, Rocuronium Requirement, Postoperative Analgesia
NCT ID: NCT01460563
Last Updated: 2011-12-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
60 participants
INTERVENTIONAL
2011-10-31
2011-12-31
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
QUADRUPLE
Study Groups
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Mg_orfil
patients preloaded with sodium valproate receives MgSO4 during the craniotomy.
Magnesium Sulfate
MgSO4 infusion: 50mg/kg bolus followed by continuous infusion
control_orfil
patients preloaded with sodium valproate receives 0.9% saline as placebo.
0.9% saline
0.9% saline as same dose as MgSO4 as placebo
0.9% saline
0.9% saline as same dose as MgSO4 as placebo
control_no orfil
patients not preloaded with sodium valproate receives 0.9% saline as placebo.
0.9% saline
0.9% saline as same dose as MgSO4 as placebo
Interventions
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Magnesium Sulfate
MgSO4 infusion: 50mg/kg bolus followed by continuous infusion
0.9% saline
0.9% saline as same dose as MgSO4 as placebo
0.9% saline
0.9% saline as same dose as MgSO4 as placebo
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* American society of anesthesiology physical status 1,2
* scheduled for elective craniotomy for aneurysm clipping or for superficial temporal artery-middle cerebral artery anastomosis
Exclusion Criteria
18 Years
65 Years
ALL
No
Sponsors
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Seoul National University Bundang Hospital
OTHER
Responsible Party
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Kim Mihyun
clinical professor
Principal Investigators
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Sanghwan Do, Doctor
Role: STUDY_CHAIR
Seoul National University Bundang Hospital
Locations
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Seoul National University Bundang hopital
Seongnam-si, Gyeonggi-do, South Korea
Countries
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Central Contacts
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Facility Contacts
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Mihyun Kim, Doctor
Role: primary
Other Identifiers
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Mg_orfil
Identifier Type: -
Identifier Source: org_study_id