Health Benefits of Chronic vs. Acute Exercise in Overweight Adults

NCT ID: NCT01452087

Last Updated: 2014-11-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

43 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-05-31

Study Completion Date

2014-10-31

Brief Summary

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Compare the effects of single session of exercise vs. chronic exercise training on key risk factors associated with Metabolic Syndrome (e.g., glucose tolerance, blood lipid profile, and blood pressure) in overweight adults.

Detailed Description

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Conditions

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Obesity

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Exercise Session

Subjects will exercise on a treadmill for 1 hour at moderate intensity (i.e., 90% of the exercise intensity found to elicit their ventilatory threshold during the preliminary testing, which is equivalent to approximately 60% of their maximal predicted heart rate).

Group Type OTHER

Exercise

Intervention Type OTHER

Subjects will exercise on a treadmill for 1 hour at moderate intensity (i.e., 90% of the exercise intensity found to elicit their ventilatory threshold during the preliminary testing, which is equivalent to approximately 60% of their maximal predicted heart rate).

Interventions

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Exercise

Subjects will exercise on a treadmill for 1 hour at moderate intensity (i.e., 90% of the exercise intensity found to elicit their ventilatory threshold during the preliminary testing, which is equivalent to approximately 60% of their maximal predicted heart rate).

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Body Mass Index: 27-34 kg/m2;
* Regular exercisers(≥4 days/wk of aerobic exercise;
* 30-60min/session at moderate and vigorous intensities);
* Non-exercisers (no regularly planned exercise/physical activity);
* Women must have regularly occurring menses and must be premenopausal.

Exclusion Criteria

* Pregnant or lactating;
* Evidence/history of cardiovascular or metabolic disease;
* Currently taking medications known to affect lipid or glucose metabolism.
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

Sponsor Role collaborator

University of Michigan

OTHER

Sponsor Role lead

Responsible Party

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JEFFREY F HOROWITZ

Associate Professor, Movement Science, School of Kinesiology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jeffrey F Horowitz, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

University of Michigan

Locations

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Substrate Metabolism Laboratory

Ann Arbor, Michigan, United States

Site Status

Countries

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United States

Other Identifiers

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R01DK077966

Identifier Type: NIH

Identifier Source: secondary_id

View Link

R01 DK077966 - R

Identifier Type: -

Identifier Source: org_study_id