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Diaphragmatic Height Index: the New Diagnostic Test for Phrenic Nerve Dysfunction

NCT ID: NCT01450917

Last Updated: 2011-10-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

245 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-09-30

Study Completion Date

2009-10-31

Brief Summary

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Diaphragmatic contraction is controlled by phrenic nerve which consists of anterior rami of 3rd- 5th cervical nerve roots. Usually, It can't be evaluated from history taking and physical examination. Thus the diaphragmatic elevation on chest radiograph is assumed to identify the phrenic nerve dysfunction. Normally, the right diaphragm is higher than the left side about 1.5 ± 0.9 centimeters or 0.5 ± 0.3 time of vertebral height. Although there are several methods to determine the diaphragmatic elevation from previous studies, the accuracy, reliability, intra and inter-observer variation are problem.

Neurotization is the effective procedure to restore upper extremity function in root avulsion type. Phrenic nerve is one of the common donor nerves which used for this procedure. But sometimes, concomitant injury of this nerve can occur. Therefore, the investigators established "Diaphragmatic height index (DHI)" from chest radiograph to use as the diagnostic test for phrenic nerve dysfunction.

Detailed Description

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Conditions

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Respiratory Paralysis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Group A

Brachial plexus injured patients with phrenic nerve dysfunction

No interventions assigned to this group

Group B

Brachial plexus injured patients without phrenic nerve dysfunction

No interventions assigned to this group

Group C

Non brachial plexus injured patients

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Brachial plexus injured patients who underwent the neurotization in our institute between 2005-2008
* Non brachial plexus injured patients who underwent the other orthopedic operation in our institute between April-June 2009

Exclusion Criteria

* Concomitant pneumothorax and/or hemothorax
* Concomitant pulmonary contusion
* Previous pulmonary disease
* Chest wall deformity
* Thoracic or thoracolumbar scoliosis (\>10 degrees)
* Hepatomegaly
* Incomplete data
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mahidol University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Saichol Wongtrakul, MD

Role: PRINCIPAL_INVESTIGATOR

Mahidol University

Other Identifiers

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Si442/2552(EC2)

Identifier Type: -

Identifier Source: org_study_id