Physical Exercise in Subjects With Juvenile Myoclonic Epilepsy
NCT ID: NCT01450423
Last Updated: 2011-10-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE2
40 participants
INTERVENTIONAL
2011-09-30
2012-05-31
Brief Summary
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It is generally approved that physical activity (PA) has a positive effect on physical as well as mental factors. However, people with epilepsy are found to be less active and PA is rarely offered or recommended as supplement to anti-epileptic medical treatment. Few studies have investigated the effect of PA in subjects with epilepsy and additional studies of high methodical quality are needed to enable evidence-based information and counselling.
This study is carried through as a randomized controlled trial which investigates the effect of participation in a 10-week cardio exercise program in people with Juvenile Myoclonic Epilepsy aged 15-50.
The study hypothesis is that participation in a 10-week cardio exercise program will induce a positive change in cognitive function (concentration and attention) and possibly in brain-derived neurotrophic factor (BDNF). In addition it is expected that the intensity and duration of the 10-week cardio exercise program is sufficient to cause changes in physiological parameters related to a reduced risk of lifestyle diseases.
Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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Physical activity
Physical activity
Participation in a 10-week supervised cardio exercise program two-three times a week. Each training session consists of 10 minutes of warm-up, 20 minutes treadmill run/walk and 30 minutes cycling. Heart rate (HR) is monitored during each session. Week 1-5: at least 15 minutes above 75% of HRmax in each session. Week 6-10: at least one session above 75% HRmax.
Control
No interventions assigned to this group
Interventions
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Physical activity
Participation in a 10-week supervised cardio exercise program two-three times a week. Each training session consists of 10 minutes of warm-up, 20 minutes treadmill run/walk and 30 minutes cycling. Heart rate (HR) is monitored during each session. Week 1-5: at least 15 minutes above 75% of HRmax in each session. Week 6-10: at least one session above 75% HRmax.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Resident: Fyen, Denmark
* Epileptic syndrome: Juvenile Myoclonic Epilepsy
Exclusion Criteria
15 Years
50 Years
ALL
No
Sponsors
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Lars Bo Andersen
OTHER
Responsible Party
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Lars Bo Andersen
Professor
Principal Investigators
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Lars Bo Andersen, Professor
Role: PRINCIPAL_INVESTIGATOR
Center of Research in Childhood Health (RICH), University of Southern Denmark
Locations
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Center of Research in Childhood Health, University of Southern Denmark
Odense, Region Syddanmark, Denmark
Epilepsy clinic, Odense University Hospital
Odense, Region Syddanmark, Denmark
Countries
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Facility Contacts
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Related Links
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Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark
Other Identifiers
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S-20110080
Identifier Type: -
Identifier Source: org_study_id